Results 41 to 50 of about 582,323 (231)

Uncovering Coenzyme Q10‐Related Genetic Determinants of Statin‐Associated Muscle Symptoms: Evidence from the UK Biobank and the All of Us Research Program

Clinical Pharmacology &Therapeutics, EarlyView.
Statin‐associated muscle symptoms (SAMS) are frequent adverse effects of statin therapy and have been hypothesized to result from impaired coenzyme Q10 (CoQ10) biosynthesis. Although genetic determinants of CoQ10 levels have been reported, genome‐wide association studies (GWASs) conducted specifically in statin users are lacking. Moreover, direct CoQ10
Da Hoon Lee, Yoon‐A Park, Yubin Song, Ji‐Min Han, Kyung Hee Choi, Myeong Gyu Kim, Hye Sun Gwak   +6 more
wiley   +1 more source

Seismic Structural Reliability by Time‐Variant Fragility Functions

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT The seismic vulnerability of aging structures is often represented in the form of fragility curves that vary with time. On one hand, each of these functions is intended to apply if the earthquake hits at the time the fragility refers to. On the other hand, performance‐based earthquake engineering (PBEE) resources to classical probabilistic ...
Iunio Iervolino
wiley   +1 more source

Geopolitics and global strategy: Making money under anarchy

Global Strategy Journal, EarlyView.
Abstract Research Summary Multinational firms conduct cross‐border trade and investment in a world of anarchy, where nation‐states must secure their survival in the absence of a world government. We develop a geopolitical‐economic order (GEO) framework to argue that the extent of geopolitical competition incentivizes states to create one of two types ...
Daniel J. Blake, Srividya Jandhyala, Quan Li   +2 more
wiley   +1 more source

Towards climate‐conscious corporate restructuring: A comparative exploration of English and Bhutanese legal frameworks

International Insolvency Review, EarlyView.
Abstract This paper conducts a comparative legal analysis of corporate restructuring frameworks in England and Bhutan, examining their capacity to integrate climate variability considerations and promote sustainable business practices. It discusses the procedural mechanisms for restructuring financially distressed enterprises available under the law of
Eugenio Vaccari, Migmar Lham
wiley   +1 more source

Rethinking law in books versus law in action in China's first experiment of a personal insolvency regime: Towards a more debtor‐oriented procedural design

International Insolvency Review, EarlyView.
Abstract Although a local experiment, the promulgation of the Regulations of Shenzhen Special Economic Zone on Personal Bankruptcy (SPBR) in 2020 was hailed as a significant milestone in China's insolvency lawmaking which has thus far addressed only corporate insolvencies.
Jenny Fu, Jin Chun
wiley   +1 more source

How Is FinTech Shaping Household Portfolio Behaviour?

International Journal of Finance &Economics, EarlyView.
ABSTRACT This paper examines how FinTech adoption influences household portfolio allocation across major advanced economies. Using a flow‐of‐funds framework and the Almost Ideal Demand System (AIDS), we model household demand for currency, deposits, loans, debt securities, and equity in the United States, United Kingdom, Euro Area, Japan and Australia.
Victor Murinde, Athina Petropoulou
wiley   +1 more source

Association Between Body Mass Index and Depression/Anxiety in an East Asian Population: A Mendelian Randomization Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Obesity and psychiatric disorders are the leading causes of global morbidity. Epidemiological studies suggest a bidirectional link between higher body mass index (BMI) and mental health outcomes, but the direction of causality remains uncertain due to confounding and reverse causation. We performed a Mendelian randomization (MR) analysis using
Perl Han Lee, Szu‐Chia Chen, Chien‐Hung Lee, Jiun‐Hung Geng, Chih‐Hung Ko   +4 more
wiley   +1 more source

The Bazaar as a Model for Knowledge Work

Knowledge and Process Management, EarlyView.
ABSTRACT This paper presents fieldwork that extends existing metaphors of knowledge work as a process shaped by hierarchical or market forces. A qualitative, ethnographic study of six knowledge‐intensive businesses in two countries identifies striking parallels with the Middle Eastern bazaar in contrast to Western impersonal markets and hierarchies. We
Reed Elliot Nelson, Andrew B. Hargadon, José Osvaldo De Sordi   +2 more
wiley   +1 more source

When a Week Is Not A Week: How Temporal Boundaries Shift Regulatory Focus and Consumer Preference

Psychology &Marketing, EarlyView.
ABSTRACT Does consumer perception of a sales event change if it falls across a calendar boundary (e.g., next month) versus within the current month, holding objective time constant? We investigate this question in the context of Cyber Monday, the global shopping event occurring the Monday after the U.S. Thanksgiving holiday.
David DeFranza, Promothesh Chatterjee
wiley   +1 more source

The Weak Core, Partition‐Based Universal Stability, and Their Risk Associations Through A Partial Order

Naval Research Logistics (NRL), EarlyView.
ABSTRACT We are concerned with the stability of a transferable‐utility cooperative (TU) game. First, the concept of core can be weakened so that the blocking of changes is limited to only those with multilateral backings. This principle of consensual blocking, as well as the traditional core‐defining one of unilateral blocking and one straddling in ...
Jian Yang
wiley   +1 more source