Results 171 to 180 of about 479,230 (336)

The Role of Serum Levels of Neurofilament Light (NfL) Chain as a Biomarker in Friedreich Ataxia

open access: yesFrontiers in Neuroscience, 2021
Bernice Frempong   +6 more
doaj   +1 more source

Efficient and Realistic Brain Simulation: A Review and Design Guide for Memristor‐Based Approaches

open access: yesAdvanced Materials Technologies, EarlyView.
Memristor‐based emulation of Hodgkin‐Huxley neuron models is investigated, by defining the ideal device characteristics needed for accurate ion‐channel representation and reviewing existing works targeting memristive replication of biological realistic neural behavior.
Lennart Paul Liong Landsmeer   +5 more
wiley   +1 more source

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

open access: yesNature, 2012
A. Biankin   +125 more
semanticscholar   +1 more source

Photoactive Monolayer MoS2 for Spiking Neural Networks Enabled Machine Vision Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Molybdenum disulfide (MoS2) optoelectronic devices are implemented as Leaky Integrate‐and‐Fire (LIF) neurons in spiking neural networks (SNNs), where light‐induced photocurrent dynamics represent potentiation (τd) and depression (τd), emulating neuronal membrane potential.
Thiha Aung   +5 more
wiley   +1 more source

Bioengineered Models of Nerve Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson   +1 more
wiley   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

open access: yesAdvanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

open access: yesAdvanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou   +16 more
wiley   +1 more source

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