Axonal protection by nicotinamide riboside with the SIRT1-AMPK pathway in TNF-induced optic nerve damage. [PDF]
Kitaoka Y +5 more
europepmc +1 more source
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su +18 more
wiley +1 more source
Differentiation timing-dependent axon targeting and subtype specification in retinal ganglion cells. [PDF]
Iwai L, Hirata T.
europepmc +1 more source
Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao +5 more
wiley +1 more source
Diverse and location-specific roles of PlexinA2, PlexinA4, and NCAM in developing hippocampal mossy fibers. [PDF]
Zhao XF +16 more
europepmc +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Mapping the secondary response to traumatic brain injury using spatial transcriptomics shows acute 4-aminopyridine treatment mitigates axonal and molecular pathology. [PDF]
Sullivan GM +8 more
europepmc +1 more source
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou +7 more
wiley +1 more source
Axonal transport impairment as an upstream mechanism in amyotrophic lateral sclerosis pathogenesis. [PDF]
Gabbay U.
europepmc +1 more source
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang +14 more
wiley +1 more source

