Results 201 to 210 of about 438,323 (349)

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

Lateralized nigrostriatal dopamine pathway activation promotes early reversal learning. [PDF]

Front Behav Neurosci
Fleps SW, Yang B, Moya NA, Wu X, Yun S, Parker JG.   +5 more
europepmc   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Axon collateralization and focal myelin dystrophy alter action potential propagation in multicompartment pyramidal neuron models. [PDF]

PLoS Comput Biol
Sengupta N, Luebke JI, Weaver CM.
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun. [PDF]

PLoS Genet
Mahata G, Chen L, Kothe GO, Rolls MM.
europepmc   +1 more source

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

, 2019
Guiping Wang, David Simon, Zhuhao Wu, Deanna M Belsky, Evan Heller, Melanie K. O’Rourke, Nicholas T. Hertz, Henrik Molina, Guisheng Zhong, Marc Tessier‐Lavigne, Xiaowei Zhuang   +10 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Modulation of axon excitable domains by astrocytes and microglia. [PDF]

Front Cell Neurosci
Garrido JJ.
europepmc   +1 more source

S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction

, 2007
Heike Stroissnigg, Alžbeta Trančíková, Luise Descovich, Jakob Fuhrmann, Waltraud Kutschera, Július Košťan, Arabella Meixner, Fatiha Nothias, Friedrich Propst   +8 more
openalex   +2 more sources