Results 201 to 210 of about 479,230 (336)

Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration. [PDF]

Sci Adv
Kiyota N, Shinozaki Y, Guo X, Kimura A, Kawamura K, Nishijima E, Honda S, Harada C, Nakazawa T, Namekata K, Harada T.   +10 more
europepmc   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source

Conduction velocity in proximal and distal portions of forelimb axons in the baboon

, 1968
J. F. M. Clough, Daniel Kernell, C. G. Phillips   +2 more
openalex   +2 more sources

Analysis of the Effects of Calcium or Magnesium on Voltage-Clamp Currents in Perfused Squid Axons Bathed in Solutions of High Potassium [PDF]

, 1969
Eduardo Rojas, Robert E. Taylor, I. Atwater, Francisco Bezanilla   +3 more
openalex   +1 more source

Molecular Biology of Axon Guidance

Neuron, 1996
M. Nieto
semanticscholar   +1 more source

Coordinated regulation of timing and strength of synaptic outputs by adrenergic receptors through control of action potentials in Purkinje cells. [PDF]

Front Cell Neurosci
Furukawa K, Kawaguchi SY.
europepmc   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

Proceedings of the National Academy of Sciences of the United States of America, 2017
G. Farías, Carlos M. A. Guardia, Raffaella De Pace, Dylan J. Britt, J. Bonifacino   +4 more
semanticscholar   +1 more source

Live Cell Imaging to Monitor Axonal Pruning in <i>Drosophila</i> Motor Neurons. [PDF]

Bio Protoc
Long K, Xu W, Miao X, Wang S, Rui M.
europepmc   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source