Results 281 to 290 of about 479,230 (336)

Axon targeting of transcriptionally distinct pioneer neurons is regulated by retinoic acid signaling. [PDF]

Nat Commun
Woodruff BM, Miller LN, Calistri NL, McVay JR, Heiser LM, Nechiporuk AV.   +5 more
europepmc   +1 more source

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

Barbiturates Block Sodium and Potassium Conductance Increases in Voltage-Clamped Lobster Axons

, 1968
Mordecai P. Blaustein
openalex   +1 more source

Metal-Based Regenerative Strategies for Peripheral Nerve Injuries: From Biodegradable Ion Source to Stable Conductive Implants. [PDF]

Biomater Res
Kim H, Rahaman KA, Kwon J, Cho S, Chung S, Han HS, Kim YC.   +6 more
europepmc   +1 more source

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Metabolic regulator LKB1 is crucial for Schwann cell–mediated axon maintenance

Nature Neuroscience, 2014
B. Beirowski, E. Babetto, J. Golden, Ying-Jr Chen, Kui Yang, R. Gross, G. Patti, J. Milbrandt   +7 more
semanticscholar   +1 more source

Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection. [PDF]

Mol Metab
Waller TJ, Collins CA, Dus M.
europepmc   +1 more source

Sequence‐ and Docking‐Site‐Dependent Contributions to Multi‐Site Phosphorylation of an Intrinsically Disordered MAPK Substrate

Advanced Science, EarlyView.
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand, Elise Delaforge, Marion Chenal, Maud Tengo, Torsten Herrmann, Juan Cortés, Pau Bernadó, Malene Ringkjøbing Jensen   +7 more
wiley   +1 more source

β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells <i>in situ</i>. [PDF]

Front Cell Neurosci
Lew V, Khetani S, Kaur S, Woodward W, Sandhu S, Rawat R, Elul T.   +6 more
europepmc   +1 more source