Results 291 to 300 of about 479,230 (336)

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

Advanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang, Jiangang Zhang, Yiran Li, Zihan Zhong, Wenhua Li, Haojun Luo, Yanyong Liu, Liujian Ouyang, Zhuoran Jiang, Yuning Sun, Hang Sun, Lulu Liu, Huayu Yang, Yu Wang, Nan Yang, Wenbin Ma, Yilei Mao   +16 more
wiley   +1 more source

Peripheral nerve injury recovery enhanced by ceftriaxone: a preclinical investigation. [PDF]

Acta Cir Bras
Gunar B, Bora ES, Topkar OM, Baysal Ö, Shammadli Z, Erbas O.   +5 more
europepmc   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

Neurodegeneration in Parkinson's disease: are we looking at the right spot? [PDF]

Mol Brain
Rocha GS, Freire MAM, Falcao D, Outeiro TF, Lima RR, Santos JR.   +5 more
europepmc   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Excitation of internally perfused squid giant axons in sodium-free media.

, 1965
Ichiji Tasaki, Irwin Singer, Akira Watanabe   +2 more
openalex   +1 more source

Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration. [PDF]

Open Biol
Xu J, Hörner M, Nagel M, Perhat P, Korneck M, Noß M, Hauser S, Schoels L, Admard J, Casadei N, Schuele R.   +10 more
europepmc   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

Advanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao, Ke Peng, Baojian Zhao, Xiaowen Meng, Gang Wang, Hanbing Xu, Li Deng, Xisheng Shan, Yichan Wang, Qiya Xu, Yanan Gao, Ruixia Weng, Hong Liu, Jin Tao, Huayue Liu, Shaoyong Song, Fuhai Ji   +16 more
wiley   +1 more source

An Analysis of the Membrane Potential along a Clamped Squid Axon

, 1961
Kenneth S. Cole
openalex   +1 more source

Unveiling the Fundamental Principles of Reconfigurable Resistance States in Silver/Poly(Ethylene Glycol) Nanofluids

Advanced Science, EarlyView.
The electrophoretic reorganization of Ag nanoparticles within a poly(ethylene glycol) leads to the formation of conductive bridges with reconfigurable resistance states. Diverse conduction characteristics of the bridge range between ohmic conduction, nonlinear tunneling, or space charge‐limited conduction, and high resistance states.
Daniil Nikitin, Kateryna Biliak, Mariia Protsak, Blessing Adejube, Suren Ali‐Ogly, Kateřina Škorvanková, Veronika Červenková, Ronaldo Katuta, Marco Tosca, Jan Hanuš, Zulfiya Černochová, Peter Černoch, Petr Štěpánek, Oleksandr Boiko, Paulina Szymoniak, Andreas Schönhals, Franz Faupel, Hynek Biederman, Alexander Vahl, Andrei Choukourov   +19 more
wiley   +1 more source