Results 301 to 310 of about 479,230 (336)

Investigating the sensitivity of the diffusion MRI signal to magnetization transfer and permeability via Monte-Carlo simulations

Zheng Z, Miller KL, Tendler BC, Cottaar M.   +3 more
europepmc   +1 more source

Transcranial Optogenetic Stimulation Promotes Corticospinal Tract Axon Regeneration to Repair Spinal Cord Injury by Activating the JAK2/STAT3 Pathway. [PDF]

Neurospine
Ma YH, Chen HY, Wei QS, Peng LZ, Zhang KJ, Deng QW, Wang LJ, Liu Z, Lai BQ, Ding Y, Li G, Jiang B, Lan Y, Zeng X, Zeng YS.   +14 more
europepmc   +1 more source

Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?

Advanced Science, EarlyView.
Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás, Domokos Meszéna, Richárd Fiáth, Andrea Slézia, István Ulbert, Gergely Katona   +5 more
wiley   +1 more source

The membrane skeleton is constitutively remodeled in neurons by calcium signaling. [PDF]

Science
Heller E, Kurup N, Zhuang X.
europepmc   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

Advanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen, Hsien‐Chung Chen, Chien‐Liang Lin, Amandeep Thakur, Raphael Onuku, I‐Chung Chen, Hao‐Yi Li, Kwang‐Yu Chang, Jian‐Ying Chuang, Wen‐Bin Yang, Hong‐Yi Lin, Yi‐Ru Shen, Jing‐Ping Liou, Wen‐Chang Chang, Tsung‐I Hsu   +14 more
wiley   +1 more source

Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration. [PDF]

Cell Regen
Sivakumar B, Hammond C, Martinez V, Joseph N, John JV, Kumar A, Krishnan A.   +6 more
europepmc   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

Advanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan, Qingyi Dai, Jianhan Ren, Lijian Jin, Weiping Wang, Zhou Ye, James Kit Hon Tsoi, Yifan Lin   +7 more
wiley   +1 more source

The Slit-Robo signalling pathway in nervous system development: a comparative perspective from vertebrates and invertebrates. [PDF]

Open Biol
Sanhueza N, Avilés EC, Oliva C.
europepmc   +1 more source

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

Advanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu, Na Zhang, Zilong Wen, Haitao Wang, Tingting Li, Runlin Ma, Menghua Li, Daxiang Wang, Haiping Shu, Xun Huang, Jianlin Han, Yiqiang Zhao, Qiuyue Liu   +12 more
wiley   +1 more source

FGF-Mediated Axon Guidance: Role of Downstream Signaling Pathways in Cytoskeletal Control. [PDF]

Cells
Li J, Gao H, Liu F.
europepmc   +1 more source