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Towards MRI axon radius mapping in clinical settings: insights from MRI-scale histology and experimental validation

Mordhorst L, Edwards L, Morozova M, Ashtarayeh M, Streubel T, Fricke B, Fritz F, Rusch H, Jäger C, Starker L, Gladytz T, Tasbihi E, Periquito J, Pohlmann A, Niendorf T, Weiskopf N, Morawski M, Mohammadi S.   +17 more
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An Active Pulse Transmission Line Simulating Nerve Axon

Proceedings of the IRE, 1962
To electronically simulate an animal nerve axon, the authors made an active pulse transmission line using tunnel diodes. The equation of propagation for this line is the same as that for a simplified model of nerve membrane treated elsewhere.
J. Nagumo, Suguru Arimoto, S. Yoshizawa
semanticscholar   +1 more source

Axonal shortening and the mechanisms of axonal motility

Cell Motility, 1988
AbstractAxons in tissue culture retract and shorten if their tips are detached from the substrate. The shortening reaction of the axon involves contractile forces that also arise during normal axonal motility, elongation, and retraction. We studied shortening in axonal segments isolated from their parent axons by transecting the axon between the growth
Raymond J. Lasek, Michael J. Katz, E. B. George, B. F. Schneider   +3 more
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Fast Axonal Transport in Squid Giant Axon

Science, 1982
Video-enhanced contrast-differential interference contrast microscopy has revealed new features of axonal transport in the giant axon of the squid, where no movement had been detected previously by conventional microscopy. The newly discovered dominant feature is vast numbers of "submicroscopic" particles, probably 30- to 50-nanometer vesicles and ...
Ichiji Tasaki, Scott T. Brady, Robert D. Allen, J. Metuzals, Susan P. Gilbert   +4 more
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Axonal transport of lipid in goldfish optic axons

Neurochemical Research, 1978
After injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. Although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported ...
Bernice Grafstein, R. M. Alpert, Mark H. Whitnall, J R Currie   +3 more
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The Molecular Biology of Axon Guidance

Science, 1996
Neuronal growth cones navigate over long distances along specific pathways to find their correct targets. The mechanisms and molecules that direct this pathfinding are the topics of this review. Growth cones appear to be guided by at least four different
M. Tessier-Lavigne, C. Goodman
semanticscholar   +1 more source

Abnormalities of the axonal cytoskeleton in giant axonal neuropathy

Journal of Neurocytology, 1988
Intermediate filaments accumulate abnormally in a variety of cell types in individuals with human inherited giant axonal neuropathy (GAN). A characteristic feature of this disorder is the occurrence of focal axonal enlargements filled with accumulations of neurofilaments.
P. K. Thomas, Michael Donaghy, Rosalind H.M. King, J. M. Workman   +3 more
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Persistence of Axonal Transport in Isolated Axons of the Mouse

European Journal of Neuroscience, 1993
AbstractWe have examined the hypothesis, for the case of mouse axons, that isolating an axon from its cell body will lead to a rapid failure of fast axonal transport as anterogradely moving organelles vacate the axon in a proximo‐distal direction, and retrogradely moving organelles vacate it in the opposite direction.
Mark A. Bisby, R. S. Smith
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