Slow axoplasmic transport under scrutiny [PDF]
Biological Research, 2011 The origin of axoplasmic proteins is central for the biology of axons. For over fifty years axons have been considered unable to synthesize proteins and that cell bodies supply them with proteins by a slow transport mechanism.
Felipe A Court, Jaime Álvarez
doaj +6 more sources
A novel antidepressant mechanism of baicalin: enhancing KIF5A-mediated axoplasmic transport and vesicular trafficking in glutamatergic neurons [PDF]
Frontiers in PharmacologyIntroductionDysfunction of axoplasmic transport is closely linked to depression. Baicalin, a major flavonoid in Scutellaria baicalensis, a well-known traditional Chinese medicine used in depression treatment, has demonstrated antidepressant-like effects ...
Shuaifei Lu +19 more
doaj +2 more sources
Advances in origin, evolution, and pathogenesis of optic disc drusen: A narrative review [PDF]
Indian Journal of OphthalmologyOptic disc drusen (ODD) is acellular calcified deposits found mainly in front of the lamina cribrosa within the optic nerve. It can cause chronic or acute vision loss.
Xiyuan Liu, Yan Yan
doaj +2 more sources
Rapid onset of neuronal death induced by blockade of either axoplasmic transport or action potentials in afferent fibers during brain development. [PDF]
, 1992 We have investigated how neurons in the optic tecta of embryonic day 16 chick embryos depend for survival on their afferents from the retina. To distinguish between activity-mediated effects and other, "trophic," ones, we compared the effects on the ...
Catsicas, M. +2 more
core +3 more sources
Axoplasmic transport in optic nerve
Indian Journal of Ophthalmology, 1982 khosla P +3 more
doaj +2 more sources
Real time monitoring peripheral nerve function with ICG and BDA-ICG by NIR-II fluorescence imaging [PDF]
Materials Today BioNeuroanatomical tract tracers are important for studying axoplasmic transport and the complex interconnections of the nervous system. Though traditional fluorescent tracers are widely used, they have several prominent drawbacks when imaging, including ...
Xiaoqi Yang +10 more
doaj +2 more sources
Pharmacology and toxicology of axoplasmic transport [PDF]
, 1984 The organized movement of cytoplasmic constituents is now recognized as a physiological process vital to the normal functioning of all cells. The importance of the ‘flow of nutrients’ for the well being of neurons and their innervated tissues was inferred as early as the mid-18th century (see quote from Prochaska, title heading).
F, Samson, J A, Donoso
openaire +3 more sources
Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
Biological Research, 2001 The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the
ALEJANDRO SERANI-MERLO
doaj +2 more sources
Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport. [PDF]
J Neurochem, 2023 Lee P +7 more
europepmc +3 more sources
What is axoplasmic transport? Considering the role of exercise training: A mini review [PDF]
Journal of Exercise & Organ Cross Talk, 2022 Like other cells in the body, nerve cells need many proteins and substances to maintain homeostasis. As we know, the transcription and translation of proteins and necessary cellular substances occurs in the cell nucleus.
Hasti Sherizadeh
doaj +1 more source