A novel antidepressant mechanism of baicalin: enhancing KIF5A-mediated axoplasmic transport and vesicular trafficking in glutamatergic neurons [PDF]
Frontiers in PharmacologyIntroductionDysfunction of axoplasmic transport is closely linked to depression. Baicalin, a major flavonoid in Scutellaria baicalensis, a well-known traditional Chinese medicine used in depression treatment, has demonstrated antidepressant-like effects ...
Shuaifei Lu +19 more
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Slow axoplasmic transport under scrutiny [PDF]
Biological Research, 2011 The origin of axoplasmic proteins is central for the biology of axons. For over fifty years axons have been considered unable to synthesize proteins and that cell bodies supply them with proteins by a slow transport mechanism.
Felipe A Court, Jaime Álvarez
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Rapid onset of neuronal death induced by blockade of either axoplasmic transport or action potentials in afferent fibers during brain development. [PDF]
, 1992 We have investigated how neurons in the optic tecta of embryonic day 16 chick embryos depend for survival on their afferents from the retina. To distinguish between activity-mediated effects and other, "trophic," ones, we compared the effects on the ...
Catsicas, M. +2 more
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Advances in origin, evolution, and pathogenesis of optic disc drusen: A narrative review [PDF]
Indian Journal of OphthalmologyOptic disc drusen (ODD) is acellular calcified deposits found mainly in front of the lamina cribrosa within the optic nerve. It can cause chronic or acute vision loss.
Xiyuan Liu, Yan Yan
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AXOPLASMIC TRANSPORT IN THE CRAYFISH NERVE CORD [PDF]
Proceedings of the National Academy of Sciences, 1969 Axoplasmic proteins in the crayfish nerve cord were labeled by the incorporation of high specific activity 3 H-leucine that was injected into one of the abdominal ganglia. The labeled proteins moved caudad as a sharply defined peak at 1.1 mm/day.
H. L. Fernandez, P. F. Davison
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Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
Biological Research, 2001 The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the
ALEJANDRO SERANI-MERLO
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Effect of vinpocetine on retrograde axoplasmic transport [PDF]
Annals of Anatomy - Anatomischer Anzeiger, 2007 Många avancerade och komplexa system används idag run-tom i världen och flera av dem är väldigt viktiga att de fungerar och fortsätter göra det. För att inte förstöra dessa system så kan en dry-run användas om någonting behöver uppdateras eller ändras ...
Knyihár-Csillik, Erzsébet +6 more
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Real time monitoring peripheral nerve function with ICG and BDA-ICG by NIR-II fluorescence imaging [PDF]
Materials Today BioNeuroanatomical tract tracers are important for studying axoplasmic transport and the complex interconnections of the nervous system. Though traditional fluorescent tracers are widely used, they have several prominent drawbacks when imaging, including ...
Xiaoqi Yang +10 more
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Axoplasmic transport of a brain-specific soluble protein☆ [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 1975 The rate and extent of axoplasmic transport of the brain-specific soluble protein (14-3-2 protein) has been investigated in the avian visual system. 1-day-old chicks were injected monocularly with tritiated proline, Incorporation of the isotope into the 14-3-2 protein synthesized within the retina of the injected eye, as well as the appearance of the ...
Marangos, Paul +3 more
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Pharmacology and toxicology of axoplasmic transport [PDF]
, 1984 The organized movement of cytoplasmic constituents is now recognized as a physiological process vital to the normal functioning of all cells. The importance of the ‘flow of nutrients’ for the well being of neurons and their innervated tissues was inferred as early as the mid-18th century (see quote from Prochaska, title heading).
J. Alejandro Donoso, Fred E. Samson
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