Results 121 to 130 of about 19,273 (245)

Real‐world treatment patterns and outcomes in accelerated and blast‐phase myeloproliferative neoplasms: Insights from a large multi‐centre cohort analysis in the United Kingdom

British Journal of Haematology, EarlyView.
Summary This UK‐based retrospective analysis describes real‐world treatment patterns and outcomes in 175 patients with accelerated (AP, n = 69) or blast‐phase (BP, n = 106) ‘Philadelphia‐negative’ myeloproliferative neoplasms (MPN‐AP/BP) diagnosed between 2013 and 2025. Median age at transformation was 71 years.
Alexandros Rampotas, Gabriel Naylor‐Layland, Clare Brown, Ahmad Alabdulkarim, Jennifer Ryan, Frances Wadelin, Samah Alimam, Phyo Wint Wint Tun, Jonathan Lambert, Jennifer O'Sullivan, Andrew J. Wilson, Laith Tafesh, Andrew McGregor, Simone Claudiani, Andrew Innes, Emily Booth, James Leveson, Steve Knapper, Mamta Garg, Mani Dubey, Theodora Vatopoulou, Charlotte Brierley, Wai Ka Natalie Leung, Graham Greenfield, Mary Frances McMullin, Alesia Khan, Kate Milne, Duncan Brian, Anna Godfrey, Claire N. Harrison, Bethan Psaila, Patrick Harrington, Amy Kirkwood, Tim C. P. Somervaille, Donal P. McLornan, on behalf of the UK Blood Cancer Research Network MPN Clinical Study Group   +35 more
wiley   +1 more source

Inducing configurational stability in inherently flexible expanded heterohelicenes and unlocking stimuli-responsive chiroptical switching. [PDF]

Chem Sci
Pal M, Karak P, Hati D, Giri M, George SJ, Choudhury J.   +5 more
europepmc   +1 more source

Synergistic induction of apoptosis by the epigenetic modulator decitabine and metformin in gastric cancer cells highlights the potential for combination therapy. [PDF]

Sci Rep
AlAli M, Latifi-Navid S, Khakzad MR.
europepmc   +1 more source

Integrated Transcriptomic and Functional Analyses Reveal lncRNA‐miRNA‐mRNA Axis in AML Relapse After Allo‐HSCT

Cancer Science, EarlyView.
Transcriptomic profiling of CD34+ cells from AML patients relapsing after allo‐HSCT reveals lncRNA‐driven ceRNA networks, with the SNHG8‐miR‐625‐ZC3H13/15 axis identified as a key relapse‐promoting module through CRISPR screening and single‐cell perturbation.
Fei Zhao, Wenhao Wang, Hongye Gao, Ping Zhu, Weihua Zhai, Yi He, Aiming Pang, Sizhou Feng, Mingzhe Han, Lina Wu, Shukai Qiao, Lei Zhang, Erlie Jiang, Xiaolei Pei, Donglin Yang   +14 more
wiley   +1 more source

Synthesis of 2-(α-trifluoromethylamino)indoles <i>via</i> stepwise cascade transformation of imidoyl sulfoxonium ylides with <i>ortho</i>-chloromethyl anilines. [PDF]

RSC Adv
Pan Y, Wang Y, Zhou X, Liu T, Zhang X, Jiang T.   +5 more
europepmc   +1 more source

MultiCOIN: Multi‐Modal COntrollable INbetweening

Computer Graphics Forum, EarlyView.
Abstract Video inbetweening creates smooth transitions between two frames making it an indispensable tool for video editing and longform video synthesis. Existing methods struggle with large or complex motion and offer limited control over intermediate frames, often misaligning with user intent.
M. Tanveer, Y. Zhou, S. Niklaus, A. Mahdavi Amiri, H. Zhang, K. K. Singh, N. Zhao   +6 more
wiley   +1 more source

Hydroxyflavone-Modified Aza-BODIPY Derivatives for Combined Photodynamic and CO Therapy against Neuroblastoma. [PDF]

J Med Chem
Kwangmettatam S, Uengwanarat B, Nabglang C, Mahingsadet K, Sritangos P, Muangsopa P, Saengboonmee C, Lai RY, Kamkaew A.   +8 more
europepmc   +1 more source

Transformative Advances in Vascular Surgery: Five Decades of Innovation in the Management of Aortic, Carotid, and Peripheral Arterial Disease

World Journal of Surgery, EarlyView.
Ghaleb A. Darwazeh, William Q. Duong, Ramola M. Panchal, Ahmed M. Abou‐Zamzam   +3 more
wiley   +1 more source

Advancing conservation breeding programs for marine invertebrates

Conservation Biology, EarlyView.
Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam, Bart Shepherd, Kylie Lev, Rebecca Albright   +3 more
wiley   +1 more source

Switchable annulation paths to diverse N-bridged bicyclic scaffolds via ligand-directed dicarbonylation. [PDF]

Nat Commun
Liu YK, Yang P, Wang LC, Bao ZP, Wu XF.
europepmc   +1 more source