Results 131 to 140 of about 19,273 (245)

Improving the use of expert opinion in disease risk analysis for conservation translocations

open access: yesConservation Biology, EarlyView.
Abstract Conservation translocations are subject to considerable uncertainty and risk, of which disease is one of the most recognized. To address disease risks, several protocols for qualitative disease risk analysis (qDRA) exist and are used for responsible conservation translocation planning.
John G. Ewen   +13 more
wiley   +1 more source

The Effect of Aza-Glycine Substitution on the Internalization of Dabcyl-Containing Short Oligoarginine. [PDF]

open access: yesBiomedicines
Tarchoun K   +5 more
europepmc   +1 more source

A multicenter performance evaluation of aztreonam-avibactam gradient diffusion susceptibility testing for <i>Enterobacterales</i>. [PDF]

open access: yesJ Clin Microbiol
Bui TI   +7 more
europepmc   +1 more source

Frailty and Fitness in Older Adults With Acute Myeloid Leukemia: From Chronological Age to Multiparametric Assessment

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Acute Myeloid Leukemia predominantly affects older adults, who often present with comorbidities, functional impairment, and frailty, limiting eligibility for intensive chemotherapy or allogeneic transplantation. Historically, treatment options were restricted to hypomethylating agents, low‐dose cytarabine, hydroxyurea, or supportive care, with
Antonella Bruzzese   +11 more
wiley   +1 more source

<i>O</i>-Vinylhydroxylamines for <i>De Novo</i> Pyrrole Synthesis. [PDF]

open access: yesJ Am Chem Soc
Randolph C   +4 more
europepmc   +1 more source

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi   +34 more
wiley   +1 more source

Synthesis of Spirocyclohexadienones with Diverse Structural Types and Ring Sizes. [PDF]

open access: yesJACS Au
Zhu Y   +7 more
europepmc   +1 more source

Pangenome analysis reveals the genetic mechanism underlying high‐altitude adaptation in Qinghai–Xizang (Tibet) Plateau Rhododendron

open access: yesJournal of Integrative Plant Biology, EarlyView.
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou   +11 more
wiley   +1 more source

Genomic variation drives plant flavor diversification

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu   +5 more
wiley   +1 more source

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