Azelaic acid alleviates UVB-induced photoaging in keratinocytes by restoring Smad-dependent TGF-β signaling. [PDF]
Lai W, Wang L, Tang W, Liu Y.
europepmc +1 more source
Flowzonolysis enables the continuous oxidative cleavage of algae‐derived palmitoleic acid to azelaic acid in a single integrated process. By combining alkene cleavage and oxidation without isolating reactive intermediates, this method minimizes auxiliary reagents, improves atom economy, and supports safer, more sustainable diacid production from ...
Caitlin Hudecek, Michael D. Burkart
wiley +1 more source
Allogeneic hematopoietic stem cell transplantation after azacitidine and venetoclax salvage in relapsed/refractory AML: a multicenter real-world study by the French AURAML group. [PDF]
Tauveron-Jalenques U +18 more
europepmc +1 more source
Ocular mucous membrane pemphigoid: A retrospective study
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer +3 more
wiley +1 more source
ABSTRACT Background and Aims There is a recognised association between inflammatory bowel disease (IBD) and lymphoma. However, the magnitude of lymphoma risk and impact of immunosuppression remain uncertain. Existing syntheses are limited by pooling of Crohn's disease (CD) and ulcerative colitis (UC) risk, conflation of disease‐ and treatment ...
Robert D. Lees +5 more
wiley +1 more source
Targeting carbapenem-resistant and hypervirulent Klebsiella pneumoniae: in vitro evaluation of cefepime/zidebactam, aztreonam/avibactam, imipenem/relebactam, and meropenem/vaborbactam. [PDF]
Li Y, Li Y, Jia X, Mao H, Li D, Zhang J.
europepmc +1 more source
Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat +8 more
wiley +1 more source
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
Access to Fused Indolines with a Quaternary <i>N</i>,<i>N</i>'-Aminal Center: Aza-Wacker-Type Cyclization for a Telescoped Reaction Sequence. [PDF]
Caselli S +4 more
europepmc +1 more source
Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese +12 more
wiley +1 more source

