Results 171 to 180 of about 19,273 (245)

Domino Polymerization for the Synthesis of Reductively Degradable Poly(disulfide)s With Arbitrary Side‐Chain Structures

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama, Ryodai Sakamoto, Atsushi Harada   +2 more
wiley   +2 more sources

Synthesis of Aza-indeno-aza-fluoranthene and Constitutional Isomers by Ring-Size Selective C-H Activation. [PDF]

Chemistry
Keck C, Rominger F, Garg S, Elstner M, Mastalerz M.   +4 more
europepmc   +1 more source

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, Volume 36, Issue 46, 8 June 2026.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

Efficacy of venetoclax combined with azacitidine for advanced blastic plasmacytoid dendritic cell neoplasm: experience from two Japanese cases. [PDF]

J Clin Exp Hematop
Shibamiya A, Ohwada C, Tsutsui Y, Tanaka A, Watanabe R, Akatsuka T, Hamada T, Sugaya M, Hayashi Y, Shiomi T, Nakaseko C.   +10 more
europepmc   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, Volume 13, Issue 32, 9 June 2026.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

HFIP-assisted Brønsted acid-catalyzed ring opening of 1-azabicyclo[1.1.0]butane to access diverse C3-quaternary aza-azetidines and indole-azetidines. [PDF]

Nat Commun
Hazra S, Tyagi A, Dutta T, Sahoo R, Bandyopadhyay B, Jindal G, Panda S.   +6 more
europepmc   +1 more source

α-Ketoglutaric acid in Ugi reactions and Ugi/aza-Wittig tandem reactions. [PDF]

Beilstein J Org Chem
Honcharov VO, Sakhno YI, Shvets OH, Saraev VE, Shishkina SV, Shcherbakova TV, Chebanov VA.   +6 more
europepmc   +1 more source

Design, Synthesis, and Antiviral Activity of 8‑Aza Fluoroneplanocin Derivatives Targeting SAH Hydrolase and Viral RdRp. [PDF]

ACS Med Chem Lett
Song J, Choi H, Kim M, Jarhad DB, Jang Y, Lee H, Kim M, Park JW, Chang TS, Aswar VR, Jeong LS.   +10 more
europepmc   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1876-1885, June 2026.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Epigenetic drug control of Clec4g/LSECtin expression reduces fibrosis burden in cirrhosis. [PDF]

Hepatol Commun
Ángel-Gomis E, Gómez-Hurtado I, Fernández-Barrena MG, Juanola O, Martínez-López S, Boix P, Ávila MA, Caparrós E, Francés R.   +8 more
europepmc   +1 more source