Results 181 to 190 of about 19,273 (245)

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley   +1 more source

Synthetic Applications of Hydroxamic Acids and Their Derivatives in Organic Chemistry. [PDF]

ACS Org Inorg Au
Wang R, Liu WH.
europepmc   +1 more source

Redox‐Neutral and Diastereoselective Cross‐Pinacol Coupling of Pyridyl Ketones With Amine‐Derived Aldehydes

ChemistryEurope, Volume 4, Issue 6, June 2026.
A redox‐neutral strategy enables cross‐selective pinacol coupling between pyridyl ketones and amine‐derived aldehydes using a samarium catalyst and visible‐light antenna ligand, affording the desired cross‐coupling products in high yields with excellent diastereoselectivity.
Takahito Kuribara, Katsuma Ando, Ayahito Kaneki, Tetsuhiro Nemoto   +3 more
wiley   +1 more source

Enantioselective Total Synthesis of Two Aromatized Halicyclamines. [PDF]

J Am Chem Soc
Firestone ZD, Grigolo TA, Pernichelle FG, Smith JM.   +3 more
europepmc   +1 more source

Tacrolimus as Single‐Agent Immunotherapy for Adult‐Onset Myasthenia Gravis: Remission, Relapse, and Safety

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Tacrolimus monotherapy yields high remission in adult‐onset MG, especially in new‐onset or younger patients. Relapse is linked to low tacrolimus concentration and rapid tapering. Hyperglycemia was the most common ADR. Long‐term use may increase cancer risk.
Zhangyan Geng, Yuting Jiang, Nairong Xie, Wenjia Zhu, Hai Chen, Yaye Wang, Haoran Liu, Qinyao Liu, Congwen Lv, Yu Qian, Yan Lu, Li Di, Min Wang, Min Xu, Xinmei Wen, Bingchuan Xie, Yuwei Da   +16 more
wiley   +1 more source

Aza-peptide aldehydes and ketones: synthesis and evaluation as human 20S proteasome inhibitors. [PDF]

Future Med Chem
Corrigan TS, Border SE, Lotti Diaz LM, Kasper KQ, Noonchester AM, Amer R, Kucway KS, Fleisher M, Fernandez JP, Lovins AR, Serrano AK, Caffrey CR, O'Donoghue AJ, Benson DM, Hadad CM, Ekici ÖD.   +15 more
europepmc   +1 more source

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

MccB‐catalyzed C‐terminal Thioesterification for Protein Bioconjugation

Current Protocols, Volume 6, Issue 6, June 2026.
Abstract Protein bioconjugation enables the installation of functional groups, probes, and payloads that cannot be genetically encoded, thereby enabling the study and manipulation of biological systems. An important class of intermediates in protein bioconjugation is C‐terminal protein α‐thioesters, which are kinetically stable yet thermodynamically ...
Di Yang, Amy M. Weeks
wiley   +1 more source

Epigenetic Remodeling in Thyroid Cancer: New Dimensions of Targeted Therapy Through lncRNA Modulation. [PDF]

Curr Issues Mol Biol
Albulescu A, Fudulu A, Mihaila MA, Iancu I, Plesa A, Bostan M, Botezatu A, Brasoveanu LI, Hotnog CM.   +8 more
europepmc   +1 more source

Evaluating the Influence of Flaxseed Oil Against Docosahexaenoic Acid on Cancer Antigen CA15‐3, Biochemical and Histopathological Parameters of DMBA‐Induced Mammary Tumors Female Albino Wistar Rats

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Flaxseed oil and docosahexaenoic acid administered to female Wistar rats with DMBA‐induced breast cancer help increase the HDL cholesterol and significantly reduce the CA15‐3, AST, ALT, LDL, and creatinine levels of rats compared to the negative control group. They also exhibited a protective effect on organs from histopathological data.
Hilda Nji Aza, Fabrice Tonfack Djikeng, Achidi Aduni Ufuan, Ines Sorelle Fotsing, Stephane Zingue   +4 more
wiley   +1 more source