Results 201 to 210 of about 5,363,495 (332)

Tipping the Scales Using Cryopreservation: Modelling the Genetic Value and Management Potential of Integrated Cryopreservation for Threatened Ex‐Situ Pupfish Populations

Animal Conservation, EarlyView.
This graphical abstract depicts the number of additional fish that would be required to achieve 90% genetic diversity for endangered pupfish species housed in EAZA collections, with or without the use of cryopreserved material. ABSTRACT Zoos and aquaria must retain genetic diversity for the species they house if the populations are to remain viable ...
James Edward Brereton, Susan L. Walker, Andrew Mooney, Pedro Machado, Elmar Fienieg, Elena Hunter   +5 more
wiley   +1 more source

Counteranion-mediated dynamic kinetic asymmetric fluorination to access sulfur-stereogenic center. [PDF]

Nat Commun
Chen Z, Tong WY, Shu J, Zhang J, Xiong X.   +4 more
europepmc   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Inhibitors of Enhancer of Zeste Homologue 2 (EZH2) as Treatment for Cancer, Autoimmune, and Other Diseases. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Characterization of Ozonation Transformation Products of Flutamide and Azathioprine by UHPLC-Ion Mobility-High-Resolution Mass Spectrometry. [PDF]

ACS ES T Water
García-Martínez J, Corpa C, Nieto G, Monte MC, Soldán P, Blanco Á, Spégel P.   +6 more
europepmc   +1 more source

Iron-Catalyzed Asymmetric NH₂-Amination of Sulfenamides. [PDF]

Angew Chem Int Ed Engl
Fan FX, Jia SM, Mo Z, Wang F.
europepmc   +1 more source

Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies. [PDF]

Clin Transl Med
Zhang J, Liu J, Zhao M, Zhang X, Liu L, Li M, Cao C, Zhang R, Zhao M.   +8 more
europepmc   +1 more source

Comparison of venetoclax and azacitidine versus a cytarabine‐based treatment for patients with acute myeloid leukaemia in first relapse after chemotherapy. A real‐world study of the DATAML‐IPC‐AURAML consortium

British Journal of Haematology, EarlyView.
Summary Complete remission (CR) rates for patients with acute myeloid leukaemia (AML) treated with intensive chemotherapy (IC) have increasingly improved. Yet, relapse remains a concern with a dismal prognosis. In this report, results are presented of a retrospective analysis comparing salvage therapy based on intermediate (I) or high (H)‐dose ...
Pierre‐Yves Dumas, Sarah Bertoli, Emilie Bérard, Clémence Santana, Maël Heiblig, Thibaut Leguay, Suzanne Tavitian, Estelle Borgne, Anne‐Charlotte de Grande, Audrey Sarry, Ziyad Acheaibi, Laetitia Largeaud, Morgane Sighieri, Emilie Klein, Emmanuelle Tavernier, Marie‐Anne Hospital, Martin Carré, Gaspar Aspas Requena, Anne Banos, Norbert Vey, Arnaud Pigneux, Christian Récher, Sylvain Garciaz   +22 more
wiley   +1 more source

Integrated in Silico and in Vitro Bioactivity Profiling of Selected South African Plant Constituents Against Carbohydrate-Metabolizing Enzymes for Type 2 Diabetes Therapy. [PDF]

Bioinform Biol Insights
Adedirin O, Sabiu S.
europepmc   +1 more source