Evolving treatments for Sjögren disease: current approaches and emerging targets
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani +3 more
wiley +1 more source
Assessing the associations between immunosuppressant use and COVID-19 severity in patients with autoimmune hepatitis. [PDF]
Rai K, Lindquist KJ, Kornak J, Ge J.
europepmc +1 more source
Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis
Immunosuppressive disease was associated with reduced overall survival, while anticoagulant use was linked to prolonged progression‐free survival in advanced cutaneous squamous cell carcinoma treated with immune checkpoint inhibitors. Host‐related factors may modulate immunotherapy efficacy and warrant prospective validation.
Glenn Geidel +27 more
wiley +1 more source
Recent developments in liver transplantation [PDF]
Brettschneider, L, Groth, CG, Starzl, TE
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European S2k guidelines on management of autoimmune blistering diseases in children and adolescents
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda +31 more
wiley +1 more source
Efficacy and Safety of Upadacitinib in a Case of Pediatric Acute Severe Ulcerative Colitis and Immune Thrombocytopenia. [PDF]
Bocchini B +6 more
europepmc +1 more source
Systematic review (51 studies; 547 patients) indicates dupilumab may unmask/worsen CTCL (mainly MF/SS). A French Delphi consensus recommends rigorous diagnostic workup, avoiding dupilumab in confirmed CTCL, discontinuing upon diagnosis, and favouring methotrexate or phototherapy.
Florent Amatore +8 more
wiley +1 more source
Refractory Penile Condyloma Acuminatum in an Elderly Man Receiving Vedolizumab and Azathioprine. [PDF]
Iwagami S, Miyai H, Nishihata M.
europepmc +1 more source
Effect of cyclosporin-A on hepatic and renal allograft mononuclear cell infiltration [PDF]
Paradis, IL, Rabin, BS, Si, L
core

