Results 1 to 10 of about 71 (66)

Evaluation of Efficacy and Safety of Combined Therapy of Melasma by using Azelic, Glycolic and Kojic Acid (Unitone and Neotone)

open access: yesDiyala Journal of Medicine, 2023
Background: Melasma is one of the most common disorders of brown hyperpigmentation, which affect primarily the face and later on some other sites of the body , seen most commonly in women during the reproductive period and may seen in men . Many options
Intisar Ahmed Hasan,   +1 more
doaj   +3 more sources

Constrained Dipeptide Surrogates: 5- and 7-Hydroxy Indolizidin-2-one Amino Acid Synthesis from Iodolactonization of Dehydro-2,8-diamino Azelates

open access: yesMolecules, 2021
The constrained dipeptide surrogates 5- and 7-hydroxy indolizidin-2-one N-(Boc)amino acids have been synthesized from L-serine as a chiral educt. A linear precursor ∆4-unsaturated (2S,8S)-2,8-bis[N-(Boc)amino]azelic acid was prepared in five steps from L-
Ramakotaiah Mulamreddy   +1 more
doaj   +2 more sources

A comparative analysis of the efficacy of a combined topical therapy in patients suffering from mild to moderate papulopustular acne

open access: yesVestnik Dermatologii i Venerologii, 2017
The goal of this study was to compare the efficacy and safety of Azelic (15% gel of azelaic acid), 1% Clindamycin gel and 0.1% Adapalene gel as a complex therapy in patients suffering from mild to moderate acne. Materials and methods.
YU. S. Kondratiyeva   +3 more
doaj   +2 more sources

Topical antibiotics for acne treatment

open access: yesVestnik Dermatologii i Venerologii, 2017
Urgency. Acne is a prevalent polymorphous multifactorial inflammatory disease with various clinical forms ranging from the mildest ones (comedonal) to the most severe forms such as phlegmonous, indurative and cystic acne.
L. V. Silina   +2 more
doaj   +2 more sources

Local treatment of chloasma in pregnant women

open access: yesVestnik Dermatologii i Venerologii, 2017
Goal. To assess the efficacy and safety of Azelic (15% gel of azelaic acid for topical administration) for the treatment of chloasma in pregnant women. Materials and methods.
N. V. Shperling   +3 more
doaj   +2 more sources

Therapy of acne: azelaic acid and basic care

open access: yesVestnik Dermatologii i Venerologii, 2017
The review covers current concepts of the pathogenesis of acne. It presents the data of international and Russian clinical studies conducted to assess the efficacy and safety of drugs comprising 15% azelaic acid and used for the treatment of acne.
K. N. Monakhov, D. K. Dombrovskaya
doaj   +1 more source

Feasibility of combination the outer antibakterialnoy therapy and preparation azelaic acid for treatment of acne

open access: yesVestnik Dermatologii i Venerologii, 2017
The review presents modern views on the pathogenesis of acne. The data of foreign and domestic clinical trials to study the efficacy and safety of drugs containing 1% clindamycin and 15% azelaic acid used to treat acne.
D. K. Dombrovskaya, K. N. Monakhov
doaj   +1 more source

Urotropin azelate: a rather unwilling co-crystal [PDF]

open access: yesActa Crystallographica Section B Structural Science, 2003
Urotropin (U) and azelaic acid (AA) form 1:1 co-crystals (UA) that give rise to a rather complex diffraction pattern, the main features of which are diffuse rods and bands in addition to the Bragg reflections. UA is characterized by solvent inclusions, parasite phases, and high vacancy and dislocation densities.
Bonin, Michel   +8 more
openaire   +4 more sources

The complex therapy of acne rosacea with azelaic acid preparations

open access: yesVestnik Dermatologii i Venerologii, 2017
The present literature data on pathogenesis and treatment of acne rosacea are reported in the article. Research results on effectiveness of therapy with azelaic acid at patients with acne rosacea are presented.
V. V. Gladko   +5 more
doaj   +1 more source

Diethyl Azelate for the Treatment of Brown Recluse Spider Bite, a Neglected Orphan Indication [PDF]

open access: yesIn Vivo, 2021
Brown recluse spider bite releases hemolytic and cytotoxic phospholipase D to the wound that may cause necrosis or even death. We examined diethyl azelate (DEA), a plasma membrane fluidizer with a broad range of immunomodulatory activities, as a potential treatment for the brown recluse spider bite.Topical DEA was used in emergency to treat brown ...
Robert T, Streeper, Elzbieta, Izbicka
openaire   +2 more sources

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