Results 1 to 10 of about 5,507 (200)

Preparation and Evaluation of Azelaic Acid Topical Microemulsion Formulation: In Vitro and In Vivo Study [PDF]

Pharmaceutics, 2021
The aim of this study was to design oil in water (O/W) microemulsion formulations for the topical administration of azelaic acid. The permeability of azelaic acid through rat skin and the anti-inflammatory activities of the formulations were conducted to
Wan-Hsuan Hung, Ping-Kang Chen, Chih-Wun Fang, Ying-Chi Lin, Pao-Chu Wu   +4 more
doaj   +3 more sources

Azelaic Acid: A Bio-Based Building Block for Biodegradable Polymers [PDF]

Polymers, 2021
The production of fine chemicals, new materials and products from renewable feedstocks represents a continuous challenge. Several procedures have been reported in the literature or patented in the last decade for the main biomass components ...
Anamaría Todea, Mariachiara Spennato, Fioretta Asaro   +2 more
exaly   +4 more sources

Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2022
Licui Li,1,2 Huixiu Lu,1,3 Yanli Zhang,4 Qian Li,4 Shaomin Shi,4 Yaling Liu1,4 1Department of Dermatology and Venereology, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Dermatology, Shijiazhuang Gaocheng People’s ...
Li L, Lu H, Zhang Y, Li Q, Shi S, Liu Y
doaj   +2 more sources

New insights into the anti-inflammatory and anti-melanoma mechanisms of action of azelaic acid and other Fusarium solani metabolites via in vitro and in silico studies [PDF]

Scientific Reports
Metabolites exploration of the ethyl acetate extract of Fusarium solani culture broth that was isolated from Euphorbia tirucalli root afforded five compounds; 4-hydroxybenzaldehyde (1), 4-hydroxybenzoic acid (2), tyrosol (3), azelaic acid (4), malic acid
Mona Ismail, Marwa H. A. Hassan, Enas I. A. Mohamed, Ahmed F. Azmy, Abeer Moawad, Rabab Mohammed, Mohamed A. Zaki   +6 more
doaj   +2 more sources

The efficacy and safety of minocycline, metronidazole, ivermectin, and azelaic acid in moderate-to-severe papulopustular rosacea: A systematic review and network meta-analysisCapsule Summary [PDF]

JAAD International
Background: There are multiple topical agents for papulopustular rosacea (PPR), but the most effective for the management of moderate-to-severe PPR remains unknown.
Esraa A. Shaheen, MD, Yara E. Aljefri, MD, Abdullah A. Ghaddaf, MD, Khalid M. Alshareef, MD, Abeer K. Alhindi, MD, Narin F. Alanazi, MD, Anwar R. Alrashidi, MD, Abdulhadi Jfri, MD, MSc   +7 more
doaj   +2 more sources

High Bio-Content Thermoplastic Polyurethanes from Azelaic Acid [PDF]

Molecules, 2022
To realize the commercialization of sustainable materials, new polymers must be generated and systematically evaluated for material characteristics and end-of-life treatment.
Bhausaheb S. Rajput, Thien An Phung Hai, Michael D. Burkart   +2 more
doaj   +2 more sources

Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, and arginine) with raloxifene [PDF]

International Journal of Pharmaceutics: X
With advancements in drug repurposing, the search for effective and less harmful anticancer agents remains a critical endeavor. Raloxifene, although not a typical anticancer drug, holds promise in this context.
Hamdy Abdelkader, Adel Al-Fatease, Ali H. Alamri, Mai E. Shoman, Hend Mohamed Abdel-Bar, Zeinab Fathalla   +5 more
doaj   +2 more sources

Ozonated Sunflower Oil Embedded within Spray-Dried Chitosan Microspheres Cross-Linked with Azelaic Acid as a Multicomponent Solid Form for Broad-Spectrum and Long-Lasting Antimicrobial Activity [PDF]

Pharmaceutics
Multicomponent solid forms for the combined delivery of antimicrobials can improve formulation performance, especially for poorly soluble drugs, by enabling the modified release of the active ingredients to better meet therapeutic needs.
Roberto Spogli, Caterina Faffa, Valeria Ambrogi, Vincenzo D’Alessandro, Gabriele Pastori   +4 more
doaj   +2 more sources

Development and Evaluation of Azelaic Acid-Loaded Microemulsion for Transfollicular Drug Delivery Through Guinea Pig Skin: A Mechanistic Study [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: Azelaic acid is a natural keratolytic, comedolytic, and antibacterial drug that is used to treat acne. The topical application of azelaic acid is associated with problems such as irritation and low permeability.
Anayatollah Salimi, Behzad Sharif Makhmal Zadeh, Salar Godazgari, Abbas Rahdar   +3 more
doaj   +1 more source

Azelaic Acid: Mechanisms of Action and Clinical Applications [PDF]

Clinical, Cosmetic and Investigational Dermatology
Feng X, Shang J, Gu Z, Gong J, Chen Y, Liu Y.   +5 more
exaly   +2 more sources