Results 221 to 230 of about 97,080 (283)

Synthesis of Hyperbranched Polyphenylenes With Controlled Molecular Weight by Suzuki–Miyaura Catalyst‐Transfer Polycondensation

Macromolecular Chemistry and Physics, Volume 227, Issue 11, 16 June 2026.
Hyperbranched polyphenylenes with controlled molecular weight and molecular weight distribution are synthesized via Suzuki–Miyaura catalyst‐transfer polycondensation using 3,5‐dibromophenylboronic acid as the monomer and 4‐bromobenzonitrile as the initiator. The molecular weight can be effectively regulated through the initiator‐to‐AB2 monomer ratio up
Mitsutoshi Jikei, Yusaku Mayumi, Kazuya Matsumoto   +2 more
wiley   +1 more source

Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis

ChemistryOpen, Volume 15, Issue 6, June 2026.
This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley   +1 more source

Research Progress on Metal‐Organic Framework Materials in Corrosion‐Resistant and Antimicrobial Metal Functional Coatings

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Metal‐organic frameworks (MOFs) hold significant potential across numerous advanced disciplines due to their exceptional properties, including high specific surface area, tunable porosity, structural diversity, and customizable functionality. Increasing attention has been directed toward employing MOFs in coatings that offer both antimicrobial
Yanchun Zhao, Yunbo Lan, Qi Chang, Fei Zhou, Yongsheng Lin, Peter K. Liaw, Peiqing La, Faqi Zhan   +7 more
wiley   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

Small Methods, Volume 10, Issue 12, 23 June 2026.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun, Isabella Vasquez, Hannah Bowman, Robert Posey, Zhongkui Hong, Joshua Tropp, Indrajit Srivastava   +6 more
wiley   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

Biological and In Silico Evaluation of Novel Methoxyphenol–1,2,3‐Triazole Hybrids as Multifunctional Anti‐Alzheimer's and Anticancer Agents

Chemical Biology &Drug Design, Volume 107, Issue 6, June 2026.
Novel methoxyphenol‐1,2,3‐triazole hybrids were synthesized as multifunctional leads. Compound 5e exhibited potent PC3 cytotoxicity (IC50: 3.57 μM), while 5c showed superior AChE inhibition (IC50: 1.44 μM) and high selectivity (SI: 6.22). DFT and docking studies confirmed their dual‐targeting potential, providing a robust scaffold for Alzheimer's and ...
Sultan Onur, Mustafa Çeşme, Ferhan Tümer   +2 more
wiley   +1 more source

Bifunctional Monosaccharides Preferentially Localize to Nuclear Subcompartments

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
Bifunctional N‐acetylgalactosamine and N‐acetylglucosamine analogues were generated and used for visualizing the subcellular localization of monosaccharides. Using these probes, we provide direct evidence for partitioning of monosaccharides into highly metabolically active nuclear subcompartments.
Pavel Barahtjan, Juan M. Iglesias‐Artola, Kristin Böhlig, Annett Lohmann, André Nadler   +4 more
wiley   +1 more source

A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase

Angewandte Chemie International Edition, Volume 65, Issue 22, 25 May 2026.
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

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Copper phosphorylated cellulose nanofibers mediated azide-alkyne cycloaddition click reaction in water.

Carbohydrate Polymers, 2023
Heterogenous copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) was performed by using the phosphorylated carbohydrate-based cellulose nanofibers loaded with copper(II) ions. The copper-containing phosphorylated cellulose nanofibers (here after
Lahoucine Bahsis, E. Ablouh, Z. Hanani, H. Sehaqui, M. El Achaby, M. Julve, Salah‐E. Stiriba   +6 more
semanticscholar   +1 more source

Asymmetric Azide-Alkyne Cycloaddition with Ir(I)/Squaramide Cooperative Catalysis: Atroposelective Synthesis of Axially Chiral Aryltriazoles.

Journal of the American Chemical Society, 2022
An Ir(I)/squaramide cooperative catalytic strategy for atroposelective synthesis of axially chiral aryltriazoles has been developed for the first time.
Xue Zhang, Shun-Xi Li, Wenjing Yu, Yufang Xie, C. Tung, Zhenghu Xu   +5 more
semanticscholar   +1 more source