Results 141 to 150 of about 1,216 (196)

The“Azirine/Oxazolone Method” under Solid-Phase Conditions

European Journal of Organic Chemistry, 2004
Aib-containing peptides have been synthesized from the N- to the C-terminus by the ‘‘azirine/oxazolone method’’ under solid-phase conditions. In this new and convenient method for the synthesis of sterically demanding peptides on solid phase, 2H-azirine ...
Heinz Heimgartner
exaly   +2 more sources

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Carbamoyl Anion Addition to Azirines

Organic Letters, 2021
The addition of carbamoyl anions to azirines affords synthetically useful 2-aziridinyl amide building blocks. The reaction scope was explored with respect to both formamide and azirine, and the addition was found to be highly diastereoselective. A one-pot conversion of a ketoxime to an aziridinyl amide was demonstrated.
Michael J. Kerner, Christian A. Kuttruff, Maxim Chevliakov, Frederic G. Buono, Donghong A. Gao, Mariusz Krawiec, Carl A. Busacca, Chris H. Senanayake, Peter Wipf, Jonathan T. Reeves   +9 more
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2H-Azirines in medicinal chemistry

Chemistry of Heterocyclic Compounds, 2021
The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.
Pavel А. Sakharov, Mikhail S. Novikov, Nikolai V. Rostovskii   +2 more
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Azirine-Based Synthesis of Alkynylpyrroles

The Journal of Organic Chemistry
A two-step method for the preparation of β-ethynylpyrroles from azirinyl ethynyl ketones by Wittig olefination, followed by FeCl2-catalyzed isomerization, has been developed. Azirines with various substitution patterns of the ring and the triple bond tolerate the reaction conditions of both steps, providing di-, tri-, and tetra-C-substituted β ...
Artur E. Taishev, Ekaterina E. Galenko, Mikhail S. Novikov, Alexander F. Khlebnikov   +3 more
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Stereoselective Allylation of Azirines with Allylindium Reagents.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tsunehisa Hirashita, Shinya Toumatsu, Yuri Imagawa, Shuki Araki, Jun-ichiro Setsune   +4 more
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ChemInform Abstract: AZIRINE PHOTOCHEMISTRY, CYCLIZATION OF 2‐STYRYL‐2H‐AZIRINES TO BENZAZEPINES

Chemischer Informationsdienst, 1974
AbstractDie Photolyse der isomeren Phenyl‐styryl‐azirine (I) führt zum Benzazepin (II), dessen Struktur durch Addition von Acetylendicarbonsäureester (III) zum Additionsprodukt (IV) bestätigt wird.
A. PADWA, J. SMOLANOFF
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Formation of Functionalized 2H-Azirines through PhIO-Mediated Trifluoroethoxylation and Azirination of Enamines

Organic Letters, 2013
A variety of enaminones and enamine carboxylic esters were converted to trifluoroethoxylated 2H-azirines through reactions with PhIO in trifluoroethanol (TFE). The cascade reaction is postulated to proceed via a PhIO-mediated oxidative trifluoroethoxylation and a subsequent azirination of the α-trifluoroethoxylated enamine intermediates.
Xiaoqian, Sun, Youran, Lyu, Daisy, Zhang-Negrerie, Yunfei, Du, Kang, Zhao   +4 more
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Reactions of azirines with N-bromosuccinimide

Tetrahedron, 1978
Abstract Reaction of 2-aryl azirines with N-bromosuccinimide in dioxane or carbon tetrachloride at −23°, affords α,α'-dibromoketones, dibromoazines, bromopyrazines, 2,5-diarylpyrazines and 3,6-diarylpyrazines.
Howard Alper, Martin Laplante
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Enantioselective Reaction of 2H‐Azirines

Chemistry – An Asian Journal, 2019
Abstract2H‐Azirines are useful precursors for the synthesis of a variety of chiral aziridine and amine derivatives with a range of biological activities. Owing to the ring strain and the presence of a C=N double bond, 2H‐azirines are more reactive than other types of ketimine, and undergo a range of enantioselective reactions, including reduction and ...
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Azirines, aziridines and related compounds

1991
Publisher Summary This chapter reviews the most significant advances in azirine and aziridine chemistry. Synthesis of 2H-azirines is discussed. The thermal rearrangement of a vinylazide can proceed by 3,5 ring closure with elimination of N2 to afford a 2H-azirine.
openaire   +1 more source