Interaction, bond formation or reaction between a dimethylamino group and an adjacent alkene or aldehyde group in aromatic systems controlled by remote molecular constraints [PDF]
, 2021 Peri-peri interactions in naphthalene systems control the degree of bond formation between a peri-dimethylamino group and a polarised alkene or aldehyde group.
Bristow, JC +3 more
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Highlighting the Rich Chemistry of the Allenone Moiety
Advanced Synthesis &Catalysis, Volume 365, Issue 9, Page 1332-1384, May 12, 2023., 2023 Abstract Conjugated and non‐conjugated allenones appear as recurring motifs in organic synthesis, natural products and mechanistic investigations showing unique properties and applications. The ability of allenones to build cycles has provided a direct access to strained systems, medium‐sized rings, arenes, heterocycles and complex polycycles.
José M. Alonso, Pedro Almendros
wiley +1 more source
The Oxford Catalogue of Opioids: A systematic synthesis of opioid drug names and their pharmacology
British Journal of Clinical Pharmacology, Volume 87, Issue 10, Page 3790-3812, October 2021., 2021 Aim The growing demand for analgesia, coupled with an increasing need to treat opioid dependence and overdose, has escalated the development of novel opioids. We aimed to quantify the number of opioid drugs developed and to catalogue them based on their pharmacology.
Georgia C. Richards +3 more
wiley +1 more source
Nature‐Inspired Functional Chromophores from Biomimetic o‐Quinone Chemistry
European Journal of Organic Chemistry, Volume 2021, Issue 21, Page 2982-2989, June 7, 2021., 2021 Bioinspired manipulation of o‐quinones generated from natural catechols represents a straightforward strategy to access the diverse molecular scaffolds endowed with peculiar functional chromophores, which offers a finely tunable palette of colors, emissions and input/output opportunities in response to pH, light, oxidant species and other external ...
Maria Laura Alfieri +4 more
wiley +1 more source
High-throughput screening of multifunctional nanocoatings based on combinations of polyphenols and catecholamines [PDF]
, 2021 Biomimetic surface coatings based on plant polyphenols and catecholamines have been used broadly in a variety of applications. However, the lack of a rational cost-effective platform for screening these coatings and their properties limits the true ...
Behboodi-Sadabad, F. +8 more
core +2 more sources
Enantioenriched alpha-Vinyl 1,4-Benzodiazepines and 1,4-Benzoxazepines via Enantioselective Rhodium-Catalyzed Hydrofunctionalizations of Alkynes and Allenes [PDF]
, 2021 Benzofused seven-membered heterocycles such as 1,4-benzo[e]diazepines (1,4-BZDs) and 1,4-benzo[e]oxazepines (1,4-BZOs) were efficiently synthesized by Rh-catalyzed hydrofunctionalization of internal alkynes and allenes in good to excellent yields.
Bernárdez Alfaya, Rodrigo +3 more
core +1 more source
Synthesis of Enantiopure Oxygen- and Nitrogen-Containing Heterocycles by Diastereoselective Ring-Closing Metathesis Reaction in Perhydro-1,3-benzoxazine Derivatives [PDF]
, 2019 Producción CientíficaDiastereoselective ring‐closing metathesis reactions on chiral trienic perhydro‐1,3‐benzoxazines derived from (−)‐8‐aminomenthol featuring two diastereotopic olefin chains is described.
Andrés Juan, Celia +4 more
core +2 more sources
Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives [PDF]
, 2016 © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).A simple ...
Bassin +9 more
core +2 more sources
An Isosteric Triaza Analogue of a Polycyclic Aromatic Hydrocarbon Monkey Saddle
Chemistry – A European Journal, Volume 26, Issue 64, Page 14560-14564, November 17, 2020., 2020 Monkey business: Isosteric exchange of CH↔N in a chiral monkey saddle makes the difference, N is increasing the conformational stability and significantly reduces the frequency of the bowl‐to‐bowl‐inversion. Abstract Since a few years, the interest in negatively‐curved fused polycyclic aromatic hydrocarbons (PAHs) has significantly increased. Recently,
Tobias Kirschbaum +2 more
wiley +1 more source
Unimolecular Variant of the Fluorescence Turn-On Oxidative Coupling of Catecholamines with Resorcinols [PDF]
, 2019 Reported herein is a unimolecular variant of the fluorescence turn-on oxidative coupling of catecholamines with resorcinols ("FluoResCat") based on the easily accessible conjugate 4-(2-((2,4-dihydroxybenzyl)amino)ethyl)benzene-1,2-diol (1).
Alessandra Napolitano +4 more
core +2 more sources