Results 261 to 270 of about 57,959 (306)
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Seminars in Respiratory and Critical Care Medicine, 2008
This is a comprehensive, clinically oriented review of the four commercially available triazoles: fluconazole, itraconazole, voriconazole, and posaconazole. Emphasis is placed in pharmacology, drug interactions, adverse events, antifungal activity, and the evolving perspective of their clinical use.
Dimitrios I, Zonios, John E, Bennett
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This is a comprehensive, clinically oriented review of the four commercially available triazoles: fluconazole, itraconazole, voriconazole, and posaconazole. Emphasis is placed in pharmacology, drug interactions, adverse events, antifungal activity, and the evolving perspective of their clinical use.
Dimitrios I, Zonios, John E, Bennett
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Clinical Infectious Diseases, 1992
The discovery of the antifungal activity of azole compounds represented an important therapeutic advance. Miconazole, ketoconazole, and fluconazole are currently commercially available, and itraconazole has undergone extensive clinical evaluation. Because of its limited activity and toxicity, miconazole has been replaced by newer agents.
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The discovery of the antifungal activity of azole compounds represented an important therapeutic advance. Miconazole, ketoconazole, and fluconazole are currently commercially available, and itraconazole has undergone extensive clinical evaluation. Because of its limited activity and toxicity, miconazole has been replaced by newer agents.
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Energetic Azolium Azolate Salts
Inorganic Chemistry, 2005Energetic salts comprising substituted imidazolium and 1,2,4-triazolium cations and 4,5-dinitro-imidazolate and 5-nitrotetrazolate anions were synthesized and characterized. On the basis of experimentally obtained heats of combustion, the calculated heats of formation range from deltaHf(o) degrees = 80 (3) to 1071 kJ/mol (13).
Hong, Xue +3 more
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Sulfonyl Azoles in the Synthesis of 3-Functionalized Azole Derivatives
The Chemical Record, 2016Sulfonyl indoles, as well as related azolyl derivatives, have been recently introduced in synthesis as stable precursors of reactive indolenine intermediates. This personal account reports on the discovery of sulfonyl azoles and their practical utilization in many synthetic processes for the preparation of functionalized 3-substituted indoles ...
PALMIERI, Alessandro, PETRINI, Marino
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Médecine et Maladies Infectieuses, 1984
Resume Les premiers azoles antifongiques possedent un spectre d'activite restreint. L'etonam (R 10100) etait actif contre les dermatophytes a la fois in vitro et in vivo par application topique. Le spectre antimycosique dans le traitement topique s'est elargi avec le miconazole et le clotrimazole.
J. Van Cutsem, P.A.J. Janssen
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Resume Les premiers azoles antifongiques possedent un spectre d'activite restreint. L'etonam (R 10100) etait actif contre les dermatophytes a la fois in vitro et in vivo par application topique. Le spectre antimycosique dans le traitement topique s'est elargi avec le miconazole et le clotrimazole.
J. Van Cutsem, P.A.J. Janssen
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Therapie, 2006
Azoles have maintained a key role in the treatment of invasive fungal infections which have a growing importance, especially in immunocompromised patients. Because of its good activity and safety, fluconazole has becoming the treatment of choice for invasive candidiasis, except those caused by Candida glabrata and C. krusei.
Michel, Wolff +2 more
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Azoles have maintained a key role in the treatment of invasive fungal infections which have a growing importance, especially in immunocompromised patients. Because of its good activity and safety, fluconazole has becoming the treatment of choice for invasive candidiasis, except those caused by Candida glabrata and C. krusei.
Michel, Wolff +2 more
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2016
Azole antifungal agents, primarily the triazoles fluconazole, itraconazole, voriconazole and posaconazole, are in widespread clinical use for the management of systemic fungal infections. Their application in the prophylaxis against and treatment of systemic mycoses continues to evolve, with ongoing advancements in drug delivery, efficacy, monitoring ...
Nicolette R. Holt, Karin A. Thursky
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Azole antifungal agents, primarily the triazoles fluconazole, itraconazole, voriconazole and posaconazole, are in widespread clinical use for the management of systemic fungal infections. Their application in the prophylaxis against and treatment of systemic mycoses continues to evolve, with ongoing advancements in drug delivery, efficacy, monitoring ...
Nicolette R. Holt, Karin A. Thursky
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