Health risks associated with infertility and non-obstructive azoospermia [PDF]
Asian Journal of AndrologyNon-obstructive azoospermia is a common condition associated with significant health risks, including increased mortality, cancer, and chronic diseases such as metabolic and cardiovascular disorders.
Eric Huyghe, Peter Ka-Fung Chiu
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Letrozole and Crocin: Protecting Leydig Cells and Modulating Androgen Receptor and CYP19 Gene Expression in Busulfan-Induced Azoospermia [PDF]
AnimalsThis study aimed to investigate the impact of letrozole and crocin on Leydig cells on busulfan-induced azoospermia using a rat model. A sample population consisting of thirty male rats was randomly assigned to five groups: (1) the control group, (2 ...
Shahrzad Nokhbeh Zaeem +3 more
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Differentiating between obstructive and non‐obstructive azoospermia: A machine learning‐based approach [PDF]
BJUI CompassBackground Infertility is a major global concern, with azoospermia, being the most severe form of male infertility. Distinguishing between obstructive azoospermia (OA) and non‐obstructive azoospermia (NOA) is crucial due to their differing treatment ...
Abdolreza Haghpanah +7 more
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Transient Azoospermia Induced by Valganciclovir Treatment for Cytomegalovirus Infection in a Reproductive Male After Kidney Transplant: A Case Report [PDF]
IJU Case ReportsIntroduction Spermatogenic dysfunction is a side effect of valganciclovir, which is commonly used to treat cytomegalovirus infections. Here, we report the case of a reproductive man who underwent kidney transplantation and was diagnosed with azoospermia ...
Kosuke Mieda +9 more
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Intact spermatogenesis in an azoospermic patient with AZFa (sY84 and sY86) microdeletion and a homozygous TG12-5T variant in CFTR [PDF]
Basic and Clinical AndrologyBackground Azoospermia, the most severe form of male infertility, is categorized into two types: non-obstructive azoospermia (NOA) and obstructive azoospermia (OA), which exhibit significant genetic heterogeneity.
Yifan Sun +5 more
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Clinician’s guide to the management of azoospermia induced by exogenous testosterone or anabolic–androgenic steroids [PDF]
Asian Journal of AndrologyAzoospermia, defined as the absence of sperm in the ejaculate, is a well-documented consequence of exogenous testosterone (ET) and anabolic–androgenic steroid (AAS) use.
Manaf Al Hashimi +3 more
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Сondition of urogenital tract microbiotes and pro- and antioxidant system in male azoospermia
Regulatory Mechanisms in Biosystems, 2021 Over the past 20 years, there has been a clear trend to increase in the number of infertile men in Ukraine, their percentage reaches 50% in infertile couples. There is a significant percentage of male infertility caused by azoospermia – the lack of sperm
M. Z. Vorobets +5 more
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Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia. [PDF]
, 2020 BACKGROUND: Tudor domain-containing proteins (TDRDs) play a critical role in piRNA biogenesis and germ cell development. piRNAs, small regulatory RNAs, act by silencing of transposons during germline development and it has recently been shown in animal ...
Aghaei, M +9 more
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Frontiers in Immunology, 2023 BackgroundAlthough more recent evidence has indicated COVID-19 is prone to azoospermia, the common molecular mechanism of its occurrence remains to be elucidated.
Jiarong He +3 more
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Frontiers in Immunology, 2023 AimThis study aimed to identify autophagy-related genes (ARGs) associated with non-obstructive azoospermia and explore the underlying molecular mechanisms.MethodsTwo datasets associated with azoospermia were downloaded from the Gene Expression Omnibus ...
Yucheng Zhong +10 more
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