Results 191 to 200 of about 35,229 (220)

Genetic mutations contributing to non-obstructive azoospermia

Best Practice & Research Clinical Endocrinology & Metabolism, 2020
Non-obstructive azoospermia is a distinct diagnosis within male infertility in which no sperm is found in the ejaculate as a result of spermatogenesis failure.
Taylor Poteet Kohn, Amin S Herati
exaly   +2 more sources

Clinical management of nonobstructive azoospermia: An update

International journal of urology, 2023
Approximately 1% of the general male population has azoospermia, and nonobstructive azoospermia accounts for the majority of cases. The causes vary widely, including chromosomal and genetic abnormalities, varicocele, drug‐induced causes, and gonadotropin
T. Takeshima, Jurii Karibe, Tomoki Saito, S. Kuroda, Mitsuru Komeya, H. Uemura, Y. Yumura   +6 more
semanticscholar   +1 more source

Genetic Architecture of Azoospermia-Time to Advance the Standard of Care.

European Urology, 2022
BACKGROUND Crypto- and azoospermia (very few/no sperm in the semen) are main contributors to male factor infertility. Genetic causes for spermatogenic failure (SPGF) include Klinefelter syndrome and Y-chromosomal azoospermia factor microdeletions, and ...
M. J. Wyrwoll, Nils Köckerling, M. Vockel, Ann-Kristin Dicke, N. Rotte, E. Pohl, J. Emich, M. Wöste, C. Rückert, R. Wabschke, J. Seggewiss, S. Ledig, A. Tewes, Yvonne Stratis, J. Cremers, J. Wistuba, C. Krallmann, S. Kliesch, A. Röpke, B. Stallmeyer, C. Friedrich, F. Tüttelmann   +21 more
semanticscholar   +1 more source

Amniotic fluid-derived exosomes improved spermatogenesis in a rat model of azoospermia.

Life Science, 2021
AIMS This study aimed to explore the therapeutic effects of amniotic fluid-derived extracellular vesicles including exosomes (AF-Exos) on the recovery of sperm production capacity in a rat model of azoospermia.
Halimeh Mobarak, M. Heidarpour, R. Rahbarghazi, M. Nouri, Mahdi Mahdipour   +4 more
semanticscholar   +1 more source

A comprehensive review of genetics and genetic testing in azoospermia

Clinics, 2013
Azoospermia due to obstructive and non-obstructive mechanisms is a common manifestation of male infertility accounting for 10-15% of such cases. Known genetic factors are responsible for approximately 1/3 of cases of azoospermia. Nonetheless, at least 40%
Sandro C. Esteves, Ashok Agarwal, Alaa J Hamada   +2 more
exaly   +2 more sources

Evaluation of immune status in testis and macrophage polarization associated with testicular damage in patients with nonobstructive azoospermia

American Journal of Reproductive Immunology, 2021
Immune cells residing in the testicular interstitial space form the immunological microenvironment of the testis. They are assumed to play a role in maintaining testicular homeostasis and immune privilege.
Wen-Zhong Zheng, Shi-Qiang Zhang, Shaoqin Jiang, Zhang-Cheng Huang, Xiaobao Chen, Huan Guo, Mengqiang Li, Song Zheng   +7 more
semanticscholar   +1 more source

Prediction of sperm extraction in non-obstructive azoospermia patients: a machine-learning perspective.

Human Reproduction, 2020
STUDY QUESTION Can a machine-learning-based model trained in clinical and biological variables support the prediction of the presence or absence of sperm in testicular biopsy in non-obstructive azoospermia (NOA) patients?
A. Zeadna, N. Khateeb, L. Rokach, Y. Lior, I. Har-Vardi, A. Harlev, Mahmoud Huleihel, E. Lunenfeld, E. Levitas   +8 more
semanticscholar   +1 more source