Results 21 to 30 of about 30,688 (283)

Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia

Andrology, 2023
Non‐invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non‐obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non‐obstructive/secretory azoospermia patients ...
S. Larriba, J. Sánchez-Herrero, R. Pluvinet, O. López‐Rodrigo, L. Bassas, L. Sumoy   +5 more
semanticscholar   +1 more source

Variant PNLDC1, Defective piRNA Processing, and Azoospermia.

New England Journal of Medicine, 2021
BACKGROUND P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expression of transposable elements and ...
L. Nagirnaja, N. Mørup, J. Nielsen, Rytis Stakaitis, Ieva Golubickaitė, M. Oud, S. Winge, F. Carvalho, K. Aston, F. Khani, Godfried W van der Heijden, C. Marques, N. Skakkebaek, E. Rajpert-De Meyts, P. Schlegel, Niels Jørgensen, J. Veltman, A. Lopes, D. Conrad, K. Almstrup   +19 more
semanticscholar   +1 more source

The significance of karyotyping and azoospermia factor analysis in patients with nonobstructive azoospermia or oligozoospermia

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: We present our study about the significance of karyotyping and azoospermia factor(AZF) analysis in patients with azoospermia or oligozoospermia.
Shin-Wen Chen, Chih-Ping Chen, Schu-Rern Chern, Yu-Ling Kuo, Chien-Ling Chiu   +4 more
doaj   +1 more source

A Case of Cystic Fibrosis in a Japanese Man With Congenital Bilateral Absence of the Vas Deferens and Recurrent Pancreatitis Caused by a Homozygous c.1210-11 T > G Variant of the Cystic Fibrosis Transmembrane Conductance Regulator Gene. [PDF]

Reprod Med Biol
ABSTRACT Case We herein report a rare case of a Japanese man diagnosed with cystic fibrosis (CF) following a workup for male infertility and recurrent pancreatitis and discuss the clinical and diagnostic implications in a population wherein CF is exceptionally rare. A 27‐year‐old Japanese man who presented with azoospermia underwent clinical evaluation,
Saito T, Kuroda S, Takeshima T, Kawahara T, Teranishi J, Karibe J, Anzai F, Tanoshima M, Makiyama K, Yumura Y.   +9 more
europepmc   +2 more sources

Whole Exome Sequencing and In Silico Analysis of Human Sertoli in Patients with Non-Obstructive Azoospermia

International Journal of Molecular Sciences, 2022
Non-obstructive azoospermia (NOA) is a serious cause of male infertility. The Sertoli cell responds to androgens and takes on roles supporting spermatogenesis, which may cause infertility.
Hossein Azizi, Danial Hashemi Karoii, T. Skutella   +2 more
semanticscholar   +1 more source

Whole‐genome sequencing identifies new candidate genes for nonobstructive azoospermia

Andrology, 2022
Genetic causes that lead to spermatogenetic failure in patients with nonobstructive azoospermia (NOA) have not been yet completely established.
A. Malcher, T. Stokowy, A. Berman, M. Olszewska, P. Jędrzejczak, D. Sielski, Adam Nowakowski, N. Rozwadowska, A. Yatsenko, M. Kurpisz   +9 more
semanticscholar   +1 more source

Using publicly available transcriptomic data to identify mechanistic and diagnostic biomarkers in azoospermia and overall male infertility

Scientific Reports, 2022
Azoospermia, which is the absence of spermatozoa in an ejaculate occurring due to defects in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men and is prevalent in up to 10–15% of infertile males.
T. Omolaoye, M. Hachim, S. D. du Plessis
semanticscholar   +1 more source

Integrative bioinformatics analysis to identify novel biomarkers associated with non-obstructive azoospermia

Frontiers in Immunology, 2023
AimThis study aimed to identify autophagy-related genes (ARGs) associated with non-obstructive azoospermia and explore the underlying molecular mechanisms.MethodsTwo datasets associated with azoospermia were downloaded from the Gene Expression Omnibus ...
Yucheng Zhong, Jun Zhao, Hao Deng, Yaqin Wu, Li Zhu, Meiqiong Yang, Qianru Liu, Guoqun Luo, Wenmin Ma, Wenmin Ma, Huan Li   +10 more
doaj   +1 more source

Differential Diagnosis of Azoospermia in Men with Infertility

Journal of Clinical Medicine, 2021
The differential diagnosis between obstructive and nonobstructive azoospermia is the first step in the clinical management of azoospermic patients with infertility. It includes a detailed medical history and physical examination, semen analysis, hormonal
D. L. Andrade, Marina C Viana, S. Esteves   +2 more
semanticscholar   +1 more source

Machine learning and integrative analysis identify the common pathogenesis of azoospermia complicated with COVID-19

Frontiers in Immunology, 2023
BackgroundAlthough more recent evidence has indicated COVID-19 is prone to azoospermia, the common molecular mechanism of its occurrence remains to be elucidated.
Jiarong He, Yuanqiao Zhao, Zhixian Zhou, Mingming Zhang   +3 more
doaj   +1 more source