Epidemic and pandemic viral infections: Impact on tuberculosis and the lung [PDF]
Major epidemics, including some that qualify as pandemics, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A (H1N1)pdm/09 and most recently COVID-19, affect the lung. Tuberculosis (TB) remains the
Delogu G. +3 more
core +9 more sources
Prediction of potential commercially inhibitors against SARS-CoV-2 by multi-task deep model [PDF]
The outbreak of novel coronavirus pneumonia (COVID-19) caused thousands of deaths worldwide, and the number of total infections is still rising. However, the development of effective vaccine for this novel virus would take a few months. Thus it is urgent
Hu, Fan, Jiang, Jiaxin, Yin, Peng
core +1 more source
Analysis of risk factors and short-term prognostic factors of arrhythmia in patients infected with mild/moderate SARS-CoV-2 Omicron variant [PDF]
BackgroundComplications, including arrhythmia, following severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection continue to be of concern. Omicron is the mainstream SARS-CoV-2 mutant circulating in mainland China.
Futao Zhang +11 more
core +1 more source
Neurological complications during the Omicron COVID-19 wave in China: A cohort study [PDF]
Background and purpose: The aim was to investigate the neurological complications associated with coronavirus disease 19 (COVID-19) during the 2022 Omicron wave.
Chen, L +15 more
core
HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies [PDF]
Human immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century.
Bissoli, Michele +4 more
core +2 more sources
Azvudine is a novel nucleoside reverse transcriptase inhibitor with antiviral activity on human immunodeficiency virus, hepatitis B virus and hepatitis C virus. Here we reported the in vitro activity of azvudine against HIV-1 and HIV-2 when used alone or
Rui-Rui Wang +11 more
doaj +1 more source
Drug repurposing in the treatment of COVID-19: A review [PDF]
The first outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was in Wuhan, Hubei, China in December 2019 and declared as a pandemic by the World Health Organization.
Madhuri, D. Game +2 more
core +2 more sources
The efficacy of azvudine in treating hospitalized COVID-19 patients: a retrospective single-center cohort analysis. [PDF]
Although coronavirus disease 2019 (COVID-19) is no longer classified as a Public Health Emergency of International Concern (PHEIC), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to undergo genetic mutations, leading to persistent public health challenges.
Lei H +8 more
europepmc +3 more sources
How COVID-19 has fundamentally changed clinical research in global health [PDF]
COVID-19 has had negative repercussions on the entire global population. Despite there being a common goal that should have unified resources and efforts, there have been an overwhelmingly large number of clinical trials that have been registered that ...
Condo, Jeanine +10 more
core +5 more sources
Remdesivir or Nirmatrelvir/Ritonavir Therapy for Omicron SARS-CoV-2 Infection in Hematological Patients and Cell Therapy Recipients [PDF]
Background: Scarce data exist that analyze the outcomes of hematological patients with SARS-CoV-2 infection during the Omicron variant period who received treatment with remdesivir or nirmatrelvir/ritonavir. Methods: This study aims to address this issue
Piñana, José Luis +28 more
core +2 more sources

