Results 71 to 80 of about 757 (146)

Data_Sheet_3_Phase III, randomized, double-blind, placebo-controlled clinical study: a study on the safety and clinical efficacy of AZVUDINE in moderate COVID-19 patients.pdf

, 2023
BackgroundIn 2019, a highly pathogenic coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surfaced and resulted in the outbreak of coronavirus disease 2019 (COVID-19).
Pingsheng Lei (5240192), Aline dos Santos Moreira (17203549), Cléber Glória Silva (17203552), Paula Gebe Abreu Cabral (6515375), Renato Martins da Silva (14787250), Antônio Brazil Viana Junior (14787268), Raul Ferraz Arruda (14787253), Sávio Bastos de Souza (6700298), Arícia Leone Evangelista Monteiro de Assis (14787259), Wim Maurits Sylvain Degrave (16933380), Junbiao Chang (1523644), Sheila Passos de Figueiredo Cabral (14787256)   +11 more
core   +1 more source

Data_Sheet_1_Phase III, randomized, double-blind, placebo-controlled clinical study: a study on the safety and clinical efficacy of AZVUDINE in moderate COVID-19 patients.PDF

, 2023
BackgroundIn 2019, a highly pathogenic coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surfaced and resulted in the outbreak of coronavirus disease 2019 (COVID-19).
Pingsheng Lei (5240192), Aline dos Santos Moreira (17203549), Cléber Glória Silva (17203552), Paula Gebe Abreu Cabral (6515375), Renato Martins da Silva (14787250), Antônio Brazil Viana Junior (14787268), Raul Ferraz Arruda (14787253), Sávio Bastos de Souza (6700298), Arícia Leone Evangelista Monteiro de Assis (14787259), Wim Maurits Sylvain Degrave (16933380), Junbiao Chang (1523644), Sheila Passos de Figueiredo Cabral (14787256)   +11 more
core   +1 more source

Real-world effectiveness of nirmatrelvir-ritonavir versus azvudine in hospitalized patients with COVID-19 during the omicron wave in Beijing: a multicenter retrospective cohort study

BMC Infectious Diseases
Background and aim Two oral antivirals (Nirmatrelvir- ritonavir and Azvudine) are widely used in China practice during the Omicron wave of the pandemic.
Xiaobo Han, Darui Gao, Chenglong Li, Xin Yuan, Junchang Cui, Weiguo Zhao, Fei Xie, Kaifei Wang, Yuhong Liu, Guoxin Muo, Na Xi, Mengli Zheng, Rentao Wang, Kun Xiao, Dahui Zhao, Xinxin Zhang, Xinjie Han, Bo Wang, Tiantian Zhang, Wuxiang Xie, Lixin Xie   +20 more
doaj   +1 more source

Construction of Minigenome Replicon of Nipah Virus and Investigation of Biological Activity. [PDF]

Viruses
Nipah virus (NiV), a highly lethal zoonotic pathogen causing encephalitis and respiratory diseases with mortality rates up to 40–70%, faces research limitations due to its strict biosafety level 4 (BSL-4) containment requirements, hindering ...
Wang F, Chen R, Zhong J, Zhou A, Peng R, Xue B, Zhou Y, Tang J, Chen X, Yang Q.   +9 more
europepmc   +2 more sources

Cover Picture: Antiviral effectiveness and safety of azvudine in hospitalized SARS‐CoV‐2 patients with pre‐existing chronic respiratory diseases: A multicenter, retrospective cohort study (View 2/2025)

VIEW, Volume 6, Issue 2, April 2025.
In the cohort of SARS‐CoV‐2 infected patients with pre‐existing chronic respiratory diseases, azvudine can not only relieve disease symptoms by blocking the activity of the viral RNA polymeraseand inhibiting viral replication, but also perform immune‐enhancing effect by increasing the number and function of serum lymphocytes, and thus activating the ...
Junyi Sun, Mengzhao Yang, Daoke Yao, Yongjian Zhou, Xiaobo Hu, Guowu Qian, Yiqiang Yuan, Silin Li, Hong Luo, Shixi Zhang, Guangming Li, Donghua Zhang, Guotao Li, Yanyang Zhang, Xinjun Hu, Zujiang Yu, Guangying Cui, Zhigang Ren   +17 more
wiley   +1 more source

Data_Sheet_2_Phase III, randomized, double-blind, placebo-controlled clinical study: a study on the safety and clinical efficacy of AZVUDINE in moderate COVID-19 patients.docx

, 2023
BackgroundIn 2019, a highly pathogenic coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surfaced and resulted in the outbreak of coronavirus disease 2019 (COVID-19).
Pingsheng Lei (5240192), Aline dos Santos Moreira (17203549), Cléber Glória Silva (17203552), Paula Gebe Abreu Cabral (6515375), Renato Martins da Silva (14787250), Antônio Brazil Viana Junior (14787268), Raul Ferraz Arruda (14787253), Sávio Bastos de Souza (6700298), Arícia Leone Evangelista Monteiro de Assis (14787259), Wim Maurits Sylvain Degrave (16933380), Junbiao Chang (1523644), Sheila Passos de Figueiredo Cabral (14787256)   +11 more
core   +1 more source

Effectiveness of the antiviral medications azvudine and nirmatrelvir-ritonavir in treating COVID-19 in patients with hematological malignancies. [PDF]

Clinics (Sao Paulo)
Background: Patients with Hematological Malignancies (HM) are at a high risk of mortality from Coronavirus disease 2019 (COVID-19). The available antivirals were different between China and other countries.
Zeng Z, Li F, Zhong M, Zhu L, Chen W, Wang X.   +5 more
europepmc   +2 more sources

Clinical characteristics, diagnosis and short‐term outcomes of COVID‐19–associated acute myocarditis in China

ESC Heart Failure, Volume 12, Issue 1, Page 338-352, February 2025.
Abstract Aims Acute myocarditis (AM) has been recognized as a rare complication of coronavirus disease 2019 (COVID‐19) infection. This study was conducted to present the clinical characteristics, disease courses and short‐term prognoses of Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) induced AM in China, which has ...
Huihui Liu, Ping Zhou, Yan Huang, Sulan Yan, Lei Zhou, Chuanyu Gao, Lian Wang, Jianjun Tang, Qiong Zhou, Xinqing Li, Xiaofeng Zhuang, Mei Zhai, Liyan Huang, Xuemei Zhao, Barry Greenberg, David H. Hsi, Yuhui Zhang, Jian Zhang   +17 more
wiley   +1 more source

Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China

Immunity, Inflammation and Disease, Volume 13, Issue 1, January 2025.
Our study provides a comprehensive depiction of the clinical symptoms experienced by healthcare workers during and after SARS‐CoV‐2 infection in China's Omicron wave, shedding light on the intricate interplay between these symptoms and offering novel insights into the physiological impact of SARS‐CoV‐2 on human health.
Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu   +11 more
wiley   +1 more source

A Retrospective Analysis of Azvudine in Patients with COVID-19 and Pre-existing Cancer

Journal of Cancer
Objectives: Azvudine has been recommended as a potential treatment for the recently discovered Coronavirus disease (COVID-19) in 2019. However, the effectiveness of Azvudine in individuals who have both COVID-19 and pre-existing cancer remains uncertain.
Li, Fangyu, Zheng, Keao, Qi, Xueyan, Cui, Kaixia, Yang, Jing, Hao, Zhiying   +5 more
openaire   +2 more sources