Results 81 to 90 of about 807 (164)

Effectiveness and Safety of Simnotrelvir/Ritonavir and Nirmatrelvir/Ritonavir in the Treatment of Moderate to Severe COVID‐19

Immunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
This is the first study comparing the effectiveness of simnotrelvir/ritonavir and nirmatrelvir/ritonavir in treating moderate and severe COVID‐19 patients. Patients who received simnotrelvir/ritonavir exhibited shorter hospitalization. Disease progression, viral clearance times, and symptom resolution time were similar between the two groups.
Xin Chen, Xiao‐Qing Lin, Fang Cheng, Shi‐Lin Zheng, Qiang Zhang, Te Wu, Xian‐Gao Jiang, Ji‐Chan Shi   +7 more
wiley   +1 more source

Fuzheng Jiedu granules against disease progression among high-risk adults with non-severe COVID-19: a multicenter retrospective cohort study [PDF]

BackgroundFuzheng Jiedu (FZJD) granules are widely used to treat coronavirus disease (COVID-19) since their market approval, but their clinical effectiveness remains uncertain.
Bo Yu, Danwen Zheng, Danwen Zheng, Danwen Zheng, Hailang He, Hanhong Zhang, Jingwei Shui, Longde Wang, Qiaoli Hua, Qing Liu, Qing Liu, Qing Liu, Qiumin Chen, Rongyuan Yang, Rongyuan Yang, Rongyuan Yang, Shengle Qin, Tong Zhang, Tong Zhang, Weng Heng, Xiaohua Xu, Xiaohua Xu, Xinghua Tan, Yang Yang, Yihang Cai, Yihang Cai, Yuntao Liu, Yuntao Liu, Yuntao Liu, Zhongde Zhang, Zhongde Zhang, Zhongde Zhang   +31 more
core   +1 more source

Putative HIV-1 reverse transcriptase inhibitors: design, synthesis, in vitro evaluation and in silico analysis. [PDF]

, 2018
Masters Degree. University of KwaZulu-Natal, Durban.One of the most significant treatments for HIV-1 infection has been the combination of drugs targeting the HIV life cycle with the aim of preventing further destruction of the host immune system. This
Poonan, Preantha.
core  

Coronavirus disease-19 : an interim evidence Synthesis of the World Association for Infectious Diseases and Immunological Disorders (Waidid) [PDF]

, 2020
Coronavirus disease 2019 (COVID-19) is a rapidly evolving, highly transmissible, and potentially lethal pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of June 11 2020, more than 7,000,000 COVID-19
Abu-Raya, Bahaa, Esposito, Susanna, Silva, Denise Rossato   +2 more
core  

Cover Picture: Antiviral effectiveness and safety of azvudine in hospitalized SARS‐CoV‐2 patients with pre‐existing chronic respiratory diseases: A multicenter, retrospective cohort study (View 2/2025)

VIEW, Volume 6, Issue 2, April 2025.
In the cohort of SARS‐CoV‐2 infected patients with pre‐existing chronic respiratory diseases, azvudine can not only relieve disease symptoms by blocking the activity of the viral RNA polymeraseand inhibiting viral replication, but also perform immune‐enhancing effect by increasing the number and function of serum lymphocytes, and thus activating the ...
Junyi Sun, Mengzhao Yang, Daoke Yao, Yongjian Zhou, Xiaobo Hu, Guowu Qian, Yiqiang Yuan, Silin Li, Hong Luo, Shixi Zhang, Guangming Li, Donghua Zhang, Guotao Li, Yanyang Zhang, Xinjun Hu, Zujiang Yu, Guangying Cui, Zhigang Ren   +17 more
wiley   +1 more source

Clinical characteristics, diagnosis and short‐term outcomes of COVID‐19–associated acute myocarditis in China

ESC Heart Failure, Volume 12, Issue 1, Page 338-352, February 2025.
Abstract Aims Acute myocarditis (AM) has been recognized as a rare complication of coronavirus disease 2019 (COVID‐19) infection. This study was conducted to present the clinical characteristics, disease courses and short‐term prognoses of Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) induced AM in China, which has ...
Huihui Liu, Ping Zhou, Yan Huang, Sulan Yan, Lei Zhou, Chuanyu Gao, Lian Wang, Jianjun Tang, Qiong Zhou, Xinqing Li, Xiaofeng Zhuang, Mei Zhai, Liyan Huang, Xuemei Zhao, Barry Greenberg, David H. Hsi, Yuhui Zhang, Jian Zhang   +17 more
wiley   +1 more source

Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China

Immunity, Inflammation and Disease, Volume 13, Issue 1, January 2025.
Our study provides a comprehensive depiction of the clinical symptoms experienced by healthcare workers during and after SARS‐CoV‐2 infection in China's Omicron wave, shedding light on the intricate interplay between these symptoms and offering novel insights into the physiological impact of SARS‐CoV‐2 on human health.
Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu   +11 more
wiley   +1 more source

Review on the Implementation and Impact of the Comprehensive and Progressive Agreement for Trans-Pacific Partnership on China\u27s Pharmaceutical Economy [PDF]

Background: The ‘Intellectual Property Rights’ chapter of the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP) sets high international standards for intellectual property rights (IPR) protection, particularly with regard to ...
Althabhawi, Nabeel M., Ashiqin Zainol, Zinatul, Cai , Xiaoqing   +2 more
core   +2 more sources

Real-world effectiveness of nirmatrelvir-ritonavir versus azvudine in hospitalized patients with COVID-19 during the omicron wave in Beijing: a multicenter retrospective cohort study

BMC Infectious Diseases
Background and aim Two oral antivirals (Nirmatrelvir- ritonavir and Azvudine) are widely used in China practice during the Omicron wave of the pandemic.
Xiaobo Han, Darui Gao, Chenglong Li, Xin Yuan, Junchang Cui, Weiguo Zhao, Fei Xie, Kaifei Wang, Yuhong Liu, Guoxin Muo, Na Xi, Mengli Zheng, Rentao Wang, Kun Xiao, Dahui Zhao, Xinxin Zhang, Xinjie Han, Bo Wang, Tiantian Zhang, Wuxiang Xie, Lixin Xie   +20 more
doaj   +1 more source

The Role of Ursodeoxycholic Acid Administration During the COVID‐19 Pandemic: A Questionnaire Survey

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
In December 2022, China classified COVID‐19 as a category B infectious disease. This ended 2 years of close epidemiological surveillance of COVID‐19. The objective of this questionnaire was to assess the infection status in the COVID‐19 pandemic since December in Henan Province, China, and the prevalence of infection in people who were taking ...
Cheng Zhou, Ran Jia, Jinqiu Yang, Tong Liu, Xiaoyan Liu, Lin Yang, Wenxia Zhao, Jess Vergis   +7 more
wiley   +1 more source