Results 101 to 110 of about 757 (146)

Identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics

There are only eight approved small molecule antiviral drugs for treating COVID-19. Among them, four are nucleotide analogues (remdesivir, JT001, molnupiravir, and azvudine), while the other four are protease inhibitors (nirmatrelvir, ensitrelvir ...
Chan, Jasper Fuk Woo, Ge, Xing Yi, Guo, Qian, Chik, Kenn Ka Heng, Yuen, Kwok Yung, Wang, Tong Yun, Xie, Yubin, Cai, Jian Piao, Cui, Sheng, Huang, Yixin, Ni, Tao, Qin, Zhenzhi, Yuan, Shuofeng, Ye, Zi Wei, Dai, Mei, Ip, Jonathan Daniel, Tsang, Jessica Oi Ling, To, Kelvin Kai Wang, Chu, Allen Wing Ho, Chan, Wan Mui, Jin, Dong Yan, Wen, Lei, Chu, Hin, Tang, Kaiming, Ong, Chon Phin, Chan, Chris Chun Yiu, Qin, Bo, Cao, Jianli   +27 more
core   +1 more source

A real-world retrospective analysis comparing the effectiveness of Azvudine and Nirmatrelvir/Ritonavir in COVID-19 patients with diabetes. [PDF]

Sci Rep
Zhu Z, Chen Q, Wang Z, Chen Q, Li X, Liu Y, Lu H, Feng J, Xie M, Dong X, Chen B, Huang J, Zeng X, Zeng Z, Yuan Y, Xu F, Liao X, Liang B, Chen W.   +18 more
europepmc   +1 more source

Commentary: A multicenter, real-world cohort study: effectiveness and safety of Azvudine in hospitalized COVID-19 patients with pre-existing diabetes. [PDF]

Front Endocrinol (Lausanne)
Guo S, Zhang J, Shu J.
europepmc   +1 more source

The efficacy of azvudine in treating hospitalized COVID-19 patients: a retrospective single-center cohort analysis. [PDF]

J Thorac Dis
Lei H, Ye YW, Zhou YJ, Mao YF, Fang Y, Chen PP, You WW, Li S, Xu YY.   +8 more
europepmc   +1 more source

Association of Azvudine with severe outcomes among hospitalized patients with COVID-19 during an omicron-dominance period in Wuhan, China: a single-center, retrospective, matched cohort study. [PDF]

BMC Infect Dis
Guo Z, Li W, Wang K, Lu Y, Gao S, Wang X, Zhao Y, Zhai Z, Chen B, Sun F, Zhao S, Cheng H.   +11 more
europepmc   +1 more source

Elbasvir Inhibits Hepatitis E Virus Internalization and, in Combination with Ribavirin, Achieves Sustained Viral Suppression In Vitro. [PDF]

Pathogens
Primadharsini PP, Nagashima S, Takahashi M, Murata K, Okamoto H.   +4 more
europepmc   +1 more source

An IRES-like cis-acting element located within the EV-A71 coding region drives translation independent of the 5'-IRES and modulates viral fitness through regulated binding of viral RNA to 3D polymerase. [PDF]

J Virol
Xing Y, Liu Q, Fu M, Zheng H, Zhao T, Chen X, Cai X, Long J-E.   +7 more
europepmc   +1 more source

Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, volume III. [PDF]

Front Pharmacol
Zhu Y, El Demerdash FM, Yang X, Machado MM, Boye A, Sun X.   +5 more
europepmc   +1 more source

Factors Influencing COVID-19 Viral Clearance: Implications for Vaccination and Antiviral Therapy. [PDF]

Infect Drug Resist
Zeng J, Xu H, Luo S, Zhou X, Li X, Zeng Y, Wang Y, Jiang H, Lin C, Zheng C, Ruan J, Yu W, Yao J, Zhao J.   +13 more
europepmc   +1 more source

Editorial: Emerging concepts for respiratory viruses after the pandemic. [PDF]

Front Cell Infect Microbiol
Dimopoulou D, Skevaki C, Can F, Morfin-Sherpa F, Fragkou PC.   +4 more
europepmc   +1 more source