Results 41 to 50 of about 640 (218)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Electronic Journal of Differential Equations, 2014 Let T be a set-valued contraction mapping on a general Banach space $\mathcal{B}$. In the first part of this paper we introduce the evolution inclusion $\dot x + x \in Tx$ and study the convergence of solutions to this inclusion toward fixed points of
Herb Kunze +3 more
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Algorithms for Molecular Biology, 2020 Background Data about herpesvirus microRNA motifs on human circular RNAs suggested the following statistical question. Consider independent random counts, not necessarily identically distributed.
John L. Spouge +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Enhanced Thermal Stability in Cu1234 Superconductor with Oxygen Annealing
CrystalsRecently, CuBa2Ca3Cu4O10+δ (Cu1234) has garnered significant interest owing to its distinctive triple-high superconducting properties (118K high Tc, combined with high Jc and high Hirr at liquid nitrogen temperature at ambient pressure) and potential for
Luchuan Shi +8 more
doaj +1 more source
Geometric Constraints and Anti-overturning Capability of a Reconfigurable Quadruped Mobile Robot
Jixie chuandong, 2022 Aiming at unmanned regions such as mine and space，a quadruped parallel mobile robot with self-recovery ability after overturning is presented. The leg structure of the quadruped robot is composed of a reconfigurable spatial six-bar mechanism，which ...
Chao Chai, Ruiqin Li
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Validation of a Bar Linkage Model for Joint Angle Estimation during Cycling
Applied Sciences, 2020 Measuring lower extremity joint angles during cycling is interesting to derive joint loading from contact forces at the pedals and to determine the cause of cycling injuries.
Sien Dieltiens +5 more
doaj +1 more source