Results 41 to 50 of about 36,513 (260)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Eight-Bar Elbow Joint Exoskeleton Mechanism
This paper deals with the design and kinematic analysis of a novel mechanism for the elbow joint of an upper-limb exoskeleton, with the aim of helping operators, in terms of effort and physical resistance, in carrying out heavy operations. In particular,
Giorgio Figliolini +3 more
doaj +1 more source
Erken Dönem Eserlerinde Âm ve Hâs Kavramları Bağlamında Fıkıh Usulünün Kelâm İlmine Etkisi [PDF]
İslâm âlimleri, Kur’an ve Sünnetteki ifadeleri metodolojik açıdan incelemiş ve kapsamlarına göre âm ve hâs olarak sınıflandırmışlardır. Ancak kelâm ekolleri bu kavramların varlığı konusunda farklı görüşler ortaya koymuştur.
Mehmet Sayğın, Mehmet Nezir Ceylan
core +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Kitab-ı Mukaddes ve Kur’an-ı Kerim’e Göre Hz. İsa
Bir araştırmanın ilmî değeri, konunun ana kaynaklarına inilmesine ve bu kaynakların önyargılardan uzak kalarak objektif usulle incelenmesine bağlıdır. Eser, merhum Prof. Dr. Salih Akdemir’in bu metotla hazırladığı “Hıristiyan Kaynaklara ve Kur’an-ı Kerim’
Akdemir, Salih
core +1 more source
Interpretations of the new LHCb $$P_c(4337)^+$$ P c ( 4337 ) + pentaquark state
Recently the LHCb Collaboration has observed a new pentaquark state, the $$P_c(4337)^+$$ P c ( 4337 ) + . Owing to its proximity to the $$\chi _{c0}(1S) p$$ χ c 0 ( 1 S ) p , $${\bar{D}}^* \varLambda _c$$ D ¯ ∗ Λ c , $${\bar{D}} \varSigma _c$$ D ¯ Σ c ...
Mao-Jun Yan +3 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Inscriptions grecques du mausolée de Hâs dit "Tombeau de Diogène" (Syrie)
Clermont-Ganneau Charles. Inscriptions grecques du mausolée de Hâs dit "Tombeau de Diogène" (Syrie). In: Comptes rendus des séances de l'Académie des Inscriptions et Belles-Lettres, 44ᵉ année, N. 2, 1900. pp.
Clermont-Ganneau, Charles Simon
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

