Results 161 to 170 of about 610,070 (288)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Clonal analysis of a case with fluid overload-associated large B-cell lymphoma evolving from primary large B-cell lymphoma of the central nervous system. [PDF]

Ann Hematol
Ito Y, Kogure Y, Maeshima AM, Hosoba R, Fukuhara S, Munakata W, Chiba K, Okada A, Shiraishi Y, Narita Y, Izutsu K, Kataoka K.   +11 more
europepmc   +1 more source

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

Advanced Science, EarlyView.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren, Zhuoqing Fang, Egor Dolzhenko, Christopher T. Saunders, Zhuanfen Cheng, Victoria Popic, Gary Peltz   +6 more
wiley   +1 more source

Large B-cell Lymphoma With IRF4 Rearrangement in the Elderly. [PDF]

Cureus
Horaguchi R, Kikuchi S, Nabe Y, Kisamori S, Minemura T, Fujihira T, Ono K, Kamihara Y, Wada A, Sato T.   +9 more
europepmc   +1 more source

A Single‐Enzyme Activated CRISPR‐Cas12a Nano System via Subtly Balanced dsDNA for Kinetic‐Gated UDG Detection and Spatiotemporal Cellular Imaging

Advanced Science, EarlyView.
Kinetic‐gated CRISPR–Cas12a activation enables single‐enzyme detection and spatiotemporal imaging of UDG ABSTRACT Uracil‐DNA glycosylase (UDG) is a key enzyme in base excision repair and an important biomarker for genomic stability and disease. In many reported sensing systems, uracil excision is coupled to signal generation through additional ...
Kejun Dong, Hao Hu, Haiyun Wang, Zijia Zheng, Shuangshuang Cheng, Wan Shu, Ruisi Liu, Xiaoyan Xin, Shiyi Huang, Dingchao Qian, Xianjin Xiao, Qiang Fu, Hongbo Wang   +12 more
wiley   +1 more source

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review). [PDF]

Int J Oncol
Wan M, Wang X, Luo B, Hong H, Zhu Y, Lin T.   +5 more
europepmc   +1 more source

Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling

Advanced Science, EarlyView.
By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu, Changming Bao, Pengyu Zhang, Tao Ding, Weiming Lin, Haodong Li, Wenjian Luo, Xizhi Deng, Hao Wang, Guanle Li, Hongyue Hu, Ye Wang, Dawei Jiang, Yu Zhang, Sisi Jia, Nan Zhang, Min Ke, Le Liang   +17 more
wiley   +1 more source

Primary Diffuse Large B-Cell Lymphoma Mimicking a Dental Abscess: A Case Report. [PDF]

Clin Case Rep
Aghdam HN, Paya L, Zohrabi M.
europepmc   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Outcomes of second-line axicabtagene ciloleucel for large B-cell lymphoma in the UK. [PDF]

Hemasphere
Kuhnl A, Kirkwood AA, Northend M, Besley C, Uttenthal B, Norman J, Hiew H, Seymour F, Maybury B, Osborne W, Sillito F, Abdulgawad A, Jones C, McCarthy P, Panopoulou A, Gribben JG, Bataillard E, Martinez-Calle N, Gajendran L, O'Reilly M, Kumar E, Wilson RP, Kasivisvanathan S, Fadlelmula N, Pryce A, Awofisayo O, Maraj A, Townsend W, Cwynarski K, Paneesha S, Mathew A, Dulobdas V, El-Sharkawi D, Creasey T, Warren M, Malladi R, Owen M, Waraich M, Ediriwickrema K, Froggatt J, Delaney A, Davies AJ, Alajangi R, Collins GP, Sanderson R, Roddie C, Menne T, Chaganti S.   +47 more
europepmc   +1 more source