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Immunology Today, 1983
B cells can influence an immune response in an antigen-specific manner by generating antibody which shuts down the response through negativefeedback. But there is growing evidence that B cells can also act upon antibody production as non-specific suppressor cells.
K M, Gilbert, M K, Hoffmann
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B cells can influence an immune response in an antigen-specific manner by generating antibody which shuts down the response through negativefeedback. But there is growing evidence that B cells can also act upon antibody production as non-specific suppressor cells.
K M, Gilbert, M K, Hoffmann
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Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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A review focussing on the lessons learned from polyclonal activation of B cells.
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New England Journal of Medicine, 1973
The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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Interleukins for B lymphocytes
Survey of Immunologic Research, 1983The above reviews our developing knowledge on the nature of B cell-specific interleu-kins. It may be anticipated that in the next several years, considerable progress will be made in understanding the physicochemical properties of these factors, their time and nature of action, and the nature of their receptors.
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B-Lymphocytes in Carcinogenesis
1979Cancer is not a single disease entity; the term is applied to a large number of diseases in which the abnormal and continued growth of cells of a given tissue is expressed. The immunologic mechanism responsible for the rejection of solid tumors in experimental animals is generally thought to be the same as that responsible for homograft rejection, i.e.,
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Antigen Receptors on B Lymphocytes
Annual Review of Immunology, 1992Recent studies on the structure of the B cell antigen receptor demonstrate that the membrane-bound and antigen-binding immunoglobulin molecules are noncovalently associated with a heterodimer of two novel transmembrane proteins. The B cell antigen receptor is thus a multicomponent receptor complex whose structural features are similar to those of the ...
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Trafficking of Adoptively Transferred B Lymphocytes in B-Lymphocyte-Deficient Mice
Journal of Experimental Biology, 1997ABSTRACT Many studies have investigated the fate of adoptively transferred lymphocytes in recipient mice, although little is known of the sites where these transferred cells reside at particular time points. Using flow cytometry, we analyzed the trafficking pattern of adoptively transferred naive B cells into the lymphoid organs of ...
R, Roth, M J, Mamula
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The Journal of Immunology, 1988
Abstract Mouse B lymphocytes were fractionated from normal T lymphocyte-depleted spleen cell populations using discontinuous percoll gradients and were stimulated with rabbit F(ab')2 anti-mouse mu-specific antibodies (anti-mu) plus the supernatant of Con A-stimulated rat spleen cells (SN) as a source of lymphokines.
F, Uher, H B, Dickler
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Abstract Mouse B lymphocytes were fractionated from normal T lymphocyte-depleted spleen cell populations using discontinuous percoll gradients and were stimulated with rabbit F(ab')2 anti-mouse mu-specific antibodies (anti-mu) plus the supernatant of Con A-stimulated rat spleen cells (SN) as a source of lymphokines.
F, Uher, H B, Dickler
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Activation of Human B Lymphocytes
The Journal of Immunology, 1977Abstract The kinetics and mechanisms of suppression of the PWM-induced PFC response of human PB lymphocytes by Con A-activated suppressor cells were investigated. It was necessary that Con A suppressor cells be present early in the preocess of activation of human B cells toward antibody synthesis, but maximal suppression of the PFC ...
Barton F. Haynes, Anthony S. Fauci
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B Lymphocyte Development in the Rabbit
International Reviews of Immunology, 1997(1997). B Lymphocyte Development in the Rabbit. International Reviews of Immunology: Vol. 15, No. 3-4, pp. 129-163.
K L, Knight, C R, Winstead
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