Results 1 to 10 of about 145,435 (136)
Compressed sensing expands the multiplexity of imaging mass cytometry [PDF]
Nature Communications, 2023 The multiplexity of current antibody-based imaging is limited by the number of reporters that can be detected simultaneously. Compressed sensing can be used to reconstruct high-dimensional information from low-dimensional measurements.
Tsuyoshi Hosogane +4 more
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Imaging mass cytometry of the immune microenvironment in alveolar echinococcosis [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundAlveolar echinococcosis (AE), caused by Echinococcus multilocularis, is a severe parasitic disease exhibiting tumor-like growth and profound immune evasion.
Yanyan Ma +21 more
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Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole-slide imaging and accurate segmentation [PDF]
Cell Reports: Methods, 2023 Summary: Imaging mass cytometry (IMC) is a powerful technique capable of detecting over 30 markers on a single slide. It has been increasingly used for single-cell-based spatial phenotyping in a wide range of samples.
Eun Na Kim +10 more
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Different approaches to Imaging Mass Cytometry data analysis. [PDF]
Bioinform Adv, 2023 Summary Imaging Mass Cytometry (IMC) is a novel, high multiplexing imaging platform capable of simultaneously detecting and visualizing up to 40 different protein targets. It is a strong asset available for in-depth study of histology and pathophysiology of the tissues.
Milosevic V.
europepmc +5 more sources
Imaging mass cytometry for high-dimensional tissue profiling in the eye [PDF]
BMC Ophthalmology, 2021 Background Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers unique advantages for the analysis of tissue samples in unprecedented detail.
Anja Schlecht +11 more
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Multidimensional profiling of drug‐treated cells by Imaging Mass Cytometry [PDF]
FEBS Open Bio, 2019 In pharmaceutical research, high‐content screening is an integral part of lead candidate development. Measuring drug response in vitro by examining over 40 parameters, including biomarkers, signaling molecules, cell morphological changes, proliferation ...
Alexandre Bouzekri +2 more
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Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research
Frontiers in Immunology, 2022 Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais +5 more
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Methods for analyzing tellurium imaging mass cytometry data.
PLoS ONE, 2019 Imaging mass cytometry (IMC) is a technique allowing visualization and quantification of over 40 biological parameters in a single experiment with subcellular spatial resolution, however most IMC experiments are limited to endpoint analysis with ...
Jay Bassan, Mark Nitz
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Cytometry Part A: the Journal of the International Society for Analytical Cytology, 2017 AbstractImaging Mass Cytometry (IMC) is an expansion of mass cytometry, but rather than analyzing single cells in suspension, it uses laser ablation to generate plumes of particles that are carried to the mass cytometer by a stream of inert gas. Images reconstructed from tissue sections scanned by IMC have a resolution comparable to light microscopy ...
Qing, Chang +5 more
exaly +3 more sources
Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies
Frontiers in Immunology, 2019 High parameter imaging is an important tool in the life sciences for both discovery and healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging (MIBI) are two relatively recent technologies which enable clinical samples to ...
Heeva Baharlou +9 more
doaj +3 more sources