Results 41 to 50 of about 5,090,386 (280)

Graph of graphs analysis for multiplexed data with application to imaging mass cytometry.

PLoS Computational Biology, 2021
Imaging Mass Cytometry (IMC) combines laser ablation and mass spectrometry to quantitate metal-conjugated primary antibodies incubated in intact tumor tissue slides.
Ya-Wei Eileen Lin, Tal Shnitzer, Ronen Talmon, Franz Villarroel-Espindola, Shruti Desai, Kurt Schalper, Yuval Kluger   +6 more
doaj   +1 more source

MALDI mass spectrometry imaging in rheumatic diseases [PDF]

, 2017
Mass spectrometry imaging (MSI) is a technique used to visualize the spatial distribution of biomolecules such as peptides, proteins, lipids or other organic compounds by their molecular masses.
Ruiz-Romero, Cristina, Cillero-Pastor, Berta, Blanco, Francisco J., Rocha, Beatriz   +3 more
core   +2 more sources

OMIP-088: Twenty-target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver. [PDF]

, 2023
The purpose of this 20-target imaging mass cytometry (IMC) panel is to identify the main cell types in formalin fixed paraffin embedded (FFPE) mouse liver tissue with the Hyperion™ mass cytometer from Standard BioTools (formerly Fluidigm).
Stroka, Deborah, Birrer, Fabienne, Fabienne Birrer, Tess Brodie, Deborah Stroka, Brodie, Tess   +5 more
core   +1 more source

Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver

JCI Insight, 2021
Studies of human hepatitis B virus (HBV) immune pathogenesis are hampered by limited access to liver tissues and technologies for detailed analyses. Here, utilizing imaging mass cytometry (IMC) to simultaneously detect 30 immune, viral, and structural ...
Daniel Traum, Yue J. Wang, Kathleen B. Schwarz, Jonathan Schug, David K.H. Wong, Harry L.A. Janssen, Norah A. Terrault, Mandana Khalili, Abdus S. Wahed, Karen F. Murray, Phillip Rosenthal, Simon C. Ling, Norberto Rodriguez-Baez, Richard K. Sterling, Daryl T.Y. Lau, Timothy M. Block, Michael D. Feldman, Elizabeth E. Furth, William M. Lee, David E. Kleiner, Anna S. Lok, Klaus H. Kaestner, Kyong-Mi Chang   +22 more
doaj   +1 more source

Automated, parallel mass spectrometry imaging and structural identification of lipids [PDF]

, 2018
We report a method that enables automated data-dependent acquisition of lipid tandem mass spectrometry data in parallel with a high-resolution mass spectrometry imaging experiment.
Mark W. Jervelund, Heeren, Ron M. A., Peter Husen, Ejsing, Christer S.; id_orcid, Eijkel, Gert B., Josch K. Pauling, Hermansson, Martin, Jervelund, Mark W., Heeren, Ron M.A., Ron M. A. Heeren, Shane R. Ellis, Martin Hermansson, Martin R. L. Paine, Ellis, Shane R., Christer S. Ejsing, Ejsing, Christer S., Paine, Martin R.L., Husen, Peter, Gert B. Eijkel, Paine, Martin R. L., Pauling, Josch K.   +20 more
core   +2 more sources

Secondary Ion Mass Spectrometry Imaging of Dictyostelium discoideum Aggregation Streams [PDF]

, 2014
High resolution imaging mass spectrometry could become a valuable tool for cell and developmental biology, but both, high spatial and mass spectral resolution are needed to enable this.
Pa��a-Toli��, Ljiljana, Smith, D.F. (Donald), Heeren, Ron M. A., Francisco A. Fern, Richard H. Gomer (214653), Richard H. Gomer, Paša-Tolić, Ljiljana, Heeren, Ron M.A., Christopher R Anderton, Gomer, R.H., Ron M A Heeren, Fernandez-Lima, Francisco A., Francisco A Fernandez-Lima, John Daniel DeBord (575199), Heeren, R.M.A. (Ron), John Daniel DeBord, Donald F Smith, Francisco A. Fernandez-Lima (575202), Fernandez-Lima, F., Smith, Donald F., Fernandez-Lima, Francisco, DeBord, John Daniel, Donald F. Smith (575200), Ljiljana Paša-Tolić, Donald F. Smith, Ron M. A. Heeren, Anderton, C.R., Ron M. A. Heeren (213370), Christopher R. Anderton, Christopher R. Anderton (575201), Ljiljana Paša-Tolić (2449252), DeBord, J.D., Richard H Gomer, Gomer, Richard H., Anderton, Christopher R., Williams, Jeffrey Graham   +35 more
core   +2 more sources

Mass Spectrometry Imaging of Microbes

, 2020
Microbes influence many aspects of human life from the environment to health, yet evaluating their biological processes at the chemical level can be problematic. Mass spectrometry imaging (MSI) enables direct evaluation of microbial chemical processes at
Yang, Hyojik, Ernst, Robert K., Goodlett, David R., Scott, Alison J.   +3 more
core   +1 more source

Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification [PDF]

, 2019
Scope In biomedical research, mass spectrometry imaging (MSI) can obtain spatially-resolved molecular information from tissue sections. Especially matrix-assisted laser desorption/ionization (MALDI) MSI offers, depending on the type of matrix, the ...
Martin-Lorenzo, Marta, McDonnell, L.A., Heeren, Ron M. A., Heeren, R.M.A., Walch, Axel, Martin-Lorenzo, M., Dewez, F., Heeren, Ron M.A., Buck, Achim, Buck, A., Walch, A.K., Balluff, B., Langer, R., Dewez, Frédéric, Balluff, Benjamin, Langer, Rupert, McDonnell, Liam A.   +16 more
core   +2 more sources

Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging

Metabolites, 2021
Osteosarcoma (OS) is the most common primary bone malignancy and largely effects adolescents and young adults, with 60% of patients under the age of 25. There are multiple cell models of OS described in vitro that express the specific genetic alterations
Lucy E. Flint, Gregory Hamm, Joseph D. Ready, Stephanie Ling, Catherine J. Duckett, Neil A. Cross, Laura M. Cole, David P. Smith, Richard J. A. Goodwin, Malcolm R. Clench   +9 more
doaj   +1 more source

Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues

, 2018
Over the last two decades, mass spectrometry imaging (MSI) has been increasingly employed to investigate the spatial distribution of a wide variety of molecules in complex biological samples.
Siegel, Tiffany Porta, Siegel, T. P., Hamm, G., Bunch, J., Bunch, Josephine, Schwamborn, Kristina, Cappell, J., Hamm, Gregory, Fletcher, John S.,, Fletcher, John S., Cappell, Jo, Schwamborn, K.   +11 more
core   +1 more source