Results 1 to 10 of about 507 (69)
Frontiers in ImmunologyMass cytometry (CyTOF) and Imaging Mass Cytometry (IMC) provide single-cell resolution for over 50 protein markers, enabling unprecedented exploration of tumour and immune heterogeneity.
Alexandre Vallée, Maxence Arutkin
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Using the power of innate immunoprofiling to understand vaccine design, infection, and immunity
Human Vaccines & Immunotherapeutics, 2023 In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors.
Jennifer Connors +11 more
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Zhongliu Fangzhi Yanjiu, 2021 Cytometry by time-of-flight (CyTOF) is an innovative single-cell analysis technique combining with mass spectrometry principles and flow cytometry. In recent years, CyTOF has been widely used in the study of leukemia treatment for its advantages of multi-
TIAN Hongjuan +4 more
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Comparative analysis of dimension reduction methods for cytometry by time-of-flight data
Nature Communications, 2023 While experimental and informatic techniques around single cell sequencing (scRNA-seq) are advanced, research around mass cytometry (CyTOF) data analysis has severely lagged behind.
Kaiwen Wang +5 more
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Removing unwanted variation with CytofRUV to integrate multiple CyTOF datasets
eLife, 2020 Mass cytometry (CyTOF) is a technology that has revolutionised single-cell biology. By detecting over 40 proteins on millions of single cells, CyTOF allows the characterisation of cell subpopulations in unprecedented detail.
Marie Trussart +5 more
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Scalable multi-sample single-cell data analysis by Partition-Assisted Clustering and Multiple Alignments of Networks. [PDF]
PLoS Computational Biology, 2017 Mass cytometry (CyTOF) has greatly expanded the capability of cytometry. It is now easy to generate multiple CyTOF samples in a single study, with each sample containing single-cell measurement on 50 markers for more than hundreds of thousands of cells ...
Ye Henry Li +6 more
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Preparation of Human Chondrocytes for Profiling Using Cytometry by Time-of-flight (cyTOF)
Bio-Protocol, 2021 Single-cell technologies have allowed high-resolution profiling of tissues and thus a deeper understanding of tissue homeostasis and disease heterogeneity. Understanding this heterogeneity can be especially important for tailoring treatments in a patient-
Fiorella Grandi, Nidhi Bhutani
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Cytomulate: accurate and efficient simulation of CyTOF data
Genome Biology, 2023 Recently, many analysis tools have been devised to offer insights into data generated via cytometry by time-of-flight (CyTOF). However, objective evaluations of these methods remain absent as most evaluations are conducted against real data where the ...
Yuqiu Yang +4 more
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Progress and applications of mass cytometry in sketching immune landscapes
Clinical and Translational Medicine, 2020 Recently emerged mass cytometry (cytometry by time‐of‐flight [CyTOF]) technology permits the identification and quantification of inherently diverse cellular systems, and the simultaneous measurement of functional attributes at the single‐cell resolution.
Ting Zhang +3 more
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Frontiers in Molecular Biosciences, 2022 Background: The pathogenesis of ulcerative colitis (UC) is closely related to immunity. The immune characteristic differences between active UC (UCa) and inactive UC (UCin) have not been completely explained.
Yongxin Luo +17 more
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