Results 21 to 30 of about 9,325 (207)
CD38hiCD19dim cells in lymph nodes predict favorable prognosis in patients with stage III melanoma receiving adjuvant PD-1-blockade [PDF]
Frontiers in OncologyBackgroundAdjuvant immune checkpoint inhibitors (ICI) have improved survival in stage III cutaneous melanoma, yet many patients do not benefit. The tumor microenvironment is pivotal for durable responses; defining cellular composition can pinpoint immune
Ieva Ailte +21 more
doaj +2 more sources
Cytokine-Stimulated Phosphoflow of Whole Blood Using CyTOF Mass Cytometry
Bio-Protocol, 2015 The ability to assess the function of a range of cytokine, antigen receptor, and Toll-like receptor (TLR) signaling pathways in a range of immune cells could provide a kind of fingerprint of the state of the human immune system.
Rosemary Fernandez, Holden Maecker
doaj +3 more sources
Immunoprofiling by CyTOF Uncovers Disease-Defining Peripheral Immune Signatures and Mechanistic Links to Renal Injury in IgA Nephropathy [PDF]
Kidney DiseasesIntroduction: The immunopathogenesis of IgA nephropathy (IgAN) involves mechanisms beyond B-cell dysregulation, yet the full spectrum and clinical relevance of peripheral immune alterations remain insufficiently defined.
Shu Qu +8 more
doaj +2 more sources
High-Dimensional Phospho-CyTOF Characterization of T-Cell Activation Responses in Whole Blood
Bio-ProtocolRecent advances in single-cell technologies have provided limited insight into the role of protein phosphorylation in T-cell fate and function. Dysregulated protein phosphorylation is associated with adverse clinical outcomes, emphasizing the need for ...
Ilyssa Ramos +9 more
doaj +2 more sources
Sample Multiplexing in CyTOF: Path To Optimize Single-Cell Proteomic Profiling
Cell SignalingSample multiplexing significantly enhanced the depth of single-cell proteomic analysis in CyTOF (Cytometry by Time-Of-Flight). New polymer-based chelators have broadened the utility of metal isotopes, enabling improved tagging and simultaneous analysis ...
Andreeff, Michael, Muftuoglu, Muharrem
core +3 more sources
Arteriosclerosis, Thrombosis, and Vascular Biology, 2017 Human monocyte subsets have traditionally been defined based on expression of CD14 and CD16 into classical, nonclassical, and intermediate monocytes. Using CyTOF, Thomas et al1 identified CCR2, CD36, HLA-DR, and CD11c as additional cell surface markers that provide better resolution of intermediate and nonclassical monocyte subsets.
P'ng, Loke, Timothy B, Niewold
openaire +2 more sources
Human CyTOF immunophenotyping.
, 2022 Human CyTOF immunophenotyping.
Xiaofeng Zhou (415920) +9 more
core +1 more source
Mouse CyTOF immunophenotyping.
, 2022 Mouse CyTOF immunophenotyping.
Xiaofeng Zhou (415920) +9 more
core +1 more source
Two CyTOF benchmark data sets for analysis.
, 2022 Two CyTOF benchmark data sets for analysis.
Lijun Cheng (3469445) +4 more
core +1 more source
, 2023 The single-cell platform CyTOF enables detection of significant changes in renal cells, especially in subsets of immune cells in ischemic human kidneys. Endogenous pro-repair cell types in RAS warrant future study for potential immune therapy.
Xiang Zhu (17086630)
core +1 more source