Results 51 to 60 of about 5,090,386 (280)

Imaging Mass Cytometry: p173

, 2020
Imaging Mass Cytometry: p173 Raw acquisitions for the paper: A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids Vito RT Zanotelli Matthias Leutenegger Xiao‐Kang Lun Fanny Georgi ...
Vito RT Zanotelli, Bernd Bodenmiller
core   +1 more source

On‐tissue chemical derivatization in mass spectrometry imaging [PDF]

, 2022
Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable tool for a wide range of applications. Matrix-assisted laser desorption/ionization (MALDI) is at the forefront of MSI ionization due to its wide availability and ...
Diego F. Cobice, Heeren, Ron M. A., Cobice, D.F., C. Logan Mackay, Simon Brockbank, Mackay, C.L., Cruickshank, Faye L., Harkin, Carla, Smith, Karl, Harkin, C., Smith, Karl W., Cruickshank, Faye, Faye L. Cruickshank, Logan Mackay, C., Cobice, Diego, Smith, K.W., Moore, T., Flinders, Bryn, Brockbank, Simon, Heeren, R.M.A., Tara Moore, Moore, Tara C. B., Cobice, Diego F., Ron M. A. Heeren, Karl W. Smith, MacKay, Logan, Carla Harkin, Cruickshank, F.L., Brockbank, S., Moore, Tara, Bryn Flinders, Heeren, Ron, Flinders, B.   +32 more
core   +1 more source

Imaging Mass Cytometry: p165

, 2020
Imaging Mass Cytometry: p165 Raw acquisitions for the paper: A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids Vito RT Zanotelli Matthias Leutenegger Xiao‐Kang Lun Fanny Georgi ...
Vito RT Zanotelli, Bernd Bodenmiller
core   +1 more source

Metal Isotope-Tagged Nanomaterials for Mass Cytometry and Imaging: Advances and Biomedical Applications

Nano Biomedicine and Engineering
Mass cytometry (cytometry by time-of-flight (CyTOF)) and imaging mass cytometry (IMC) are transformative technologies that combine flow cytometry principles with time-of-flight mass spectrometry (TOF-MS).
Dongling Jia, Minhui Cui, Weiwei Wang, Jielin Sun, Xiaoxiang Chen   +4 more
doaj   +1 more source

Automatic Generic Registration of Mass Spectrometry Imaging Data to Histology Using Nonlinear Stochastic Embedding

, 2014
The combination of mass spectrometry imaging and histology has proven a powerful approach for obtaining molecular signatures from specific cells/tissues of interest, whether to identify biomolecular changes associated with specific histopathological ...
Dijkstra, J., McDonnell, L.A., Heeren, Ron M. A., Abdelmoula, W.M., Dijkstra, Jouke, Maaten, L. van der, Heeren, R.M.A., Lelieveldt, Boudewijn P. F., Abdelmoula, Walid M., Morreau, Hans, Lelieveldt, B.P.F., Skraskova, Karolina, Tolner, Else A., Skraskova, K., Morreau, H., van der Maaten, Laurens, Carreira, R.J., Balluff, B., Tolner, E.A., Maagdenberg, A.M.J.M. van den, van den Maagdenberg, Arn M. J. M., Balluff, Benjamin, McDonnell, Liam A., Carreira, Ricardo J.   +23 more
core   +1 more source

Ultra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

, 2020
Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy, and dynamic range ...
Blakney, Greg T., Ellis, Shane R., Heeren, Ron M. A., Smith, Donald F., Bowman, Andrew P., Hendrickson, Christopher L.   +5 more
core   +1 more source

Imaging Mass Cytometry Data Acquisition v1 [PDF]

, 2020
This SOP describes the image acquisition with an Imaging Mass Cytometer (IMC or Hyperion). Prior to this protocol the IMC needs to be fully tuned to specifications (see “HuBMAP_Protocol_4_IMC_Tuning.pdf”). Additionally, every batch of samples stained with the same antibody-mix requires the acquisition of a compensation slide for spill over correction ...
Michelle Daniel, Marda Jorgensen
openaire   +1 more source

Faster raster matrix-assisted laser desorption/ionization mass spectrometry imaging of lipids at high lateral resolution [PDF]

, 2019
The clinical use of mass spectrometry imaging (MSI) is rapidly growing, and applications are expanding. Crucially, the analysis of clinical cohorts requires a combination of higher analytical throughput and higher lateral resolution. Here, we demonstrate
Siegel, Tiffany Porta, Dewez, Frederic, Cillero-Pastor, Berta, Murray, Paul, Barre, Florian, Towers, Mark, Claude, Emmanuelle, Heeren, Ron, Rocha, Beatriz   +8 more
core   +2 more sources

Novel Techniques and Future Perspective for Investigating Critical-Size Bone Defects

Bioengineering, 2022
A critical-size bone defect is a challenging clinical problem in which a gap between bone ends will not heal and will become a nonunion. The current treatment is to harvest and transplant an autologous bone graft to facilitate bone bridging.
Elijah Ejun Huang, Ning Zhang, Huaishuang Shen, Xueping Li, Masahiro Maruyama, Takeshi Utsunomiya, Qi Gao, Roberto A. Guzman, Stuart B. Goodman   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source