Results 31 to 40 of about 5,090,386 (280)

Fast Mass Microscopy: Mass Spectrometry Imaging of a Gigapixel Image in 34 Minutes

, 2022
[Image: see text] Mass spectrometry imaging (MSI) maps the spatial distributions of chemicals on surfaces. MSI requires improvements in throughput and spatial resolution, and often one is compromised for the other. In microprobe-mode MSI, improvements in
Claes, Britt S. R., Heeren, Ron M. A., Claes, Britt S R, Heeren, Ron M A, Körber, Aljoscha, Anthony, Ian G. M., Keelor, Joel D., Ron M. A. Heeren, Keelor, Joel D, Britt S. R. Claes, Joel D. Keelor, Aljoscha Körber, Ian G. M. Anthony, Anthony, Ian G M   +13 more
core   +1 more source

Imaging Mass Cytometry Analysis of immune Checkpoint Inhibitor-Related Pneumonitis: A Case Report

Frontiers in Immunology, 2022
Immune checkpoint inhibitor-related pneumonitis (CIP) is a rare but well-recognized immune-related adverse event (irAE), causes 35% of irAE related deaths.
Yuan Cheng, Xiao-Ming Wang, Qin Hu, Kunyan Sun, Xiang Zhao, Meng Zhang, Guangfa Wang, He Wang, Yan Xiong   +8 more
doaj   +1 more source

Mass Cytometric Analysis of Early-Stage Mycosis Fungoides

Cells, 2022
Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Early-stage disease is characterized by superficial infiltrates of small- to medium-sized atypical epidermotropic T lymphocytes that are clonal related.
Nannan Guo, Li Jia, Coby Out-Luiting, Noel F. C. C. de Miranda, Rein Willemze, Frits Koning, Maarten Vermeer, Koen Quint   +7 more
doaj   +1 more source

Development of 42 marker panel for in-depth study of cancer associated fibroblast niches in breast cancer using imaging mass cytometry [PDF]

Frontiers in Immunology
Kenneth Finne, Vladan Milosevic, Lars A Akslen   +2 more
exaly   +2 more sources

High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue. [PDF]

, 2016
Formalin-fixed and paraffin-embedded (FFPE) tissue specimens are the gold standard for histological examination, and they provide valuable molecular information in tissue-based research.
McDonnell, L.A., Kuppen, P.J.K., Ly, A., Velde, C.J.H. van de, Kuppen, P.J., Kuppen, Peter J K, Buck, Achim, van de Velde, Cornelis J. H., Walch, A.K., Langer, R., Feuchtinger, A., Walch, A., Sun, Na, Janssen, Klaus-Peter, Balluff, Benjamin, Gorzolka, Karin, Weirich, Gregor, Langer, Rupert, Erlmeier, Franziska, Kuppen, Peter J. K., Aubele, M., Weirich, G., McDonnell, Liam, Walch, Axel, Zitzelsberger, Horst, Erlmeier, F., Ly, Alice, Sun, N., van de Velde, Cornelis J H, Aichler, Michaela, Buck, A., van de Velde, C.J., Feuchtinger, Annette, Zitzelsberger, H., Balluff, B., Aichler, M., McDonnell, L., Janssen, K.P., Aubele, Michaela, Gorzolka, K.   +39 more
core   +1 more source

Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease

npj Parkinson's Disease, 2021
Here we report the application of a mass spectrometry-based technology, imaging mass cytometry, to perform in-depth proteomic profiling of mitochondrial complexes in single neurons, using metal-conjugated antibodies to label post-mortem human midbrain ...
Chun Chen, David McDonald, Alasdair Blain, Ashwin Sachdeva, Laura Bone, Anna L. M. Smith, Charlotte Warren, Sarah J. Pickett, Gavin Hudson, Andrew Filby, Amy E. Vincent, Doug M. Turnbull, Amy K. Reeve   +12 more
doaj   +1 more source

Tissue Staining for Imaging Mass Cytometry v1 [PDF]

, 2021
This protocol describes the preparation and staining of human FFPE material for multiplex visualization using Imaging Mass Cytometry (IMC). This protocol uses basic standard immunohistochemical staining techniques. The tissue is incubated with antibodies that have specific affinity for different cells and tissues in the context of a formalin fixed ...
John Herndon, Madelyn Carmody, Stephen Oh, not provided William Gillanders Washington University St Louis   +3 more
openaire   +1 more source

MATISSE: a method for improved single cell segmentation in imaging mass cytometry

BMC Biology, 2021
Background Visualizing and quantifying cellular heterogeneity is of central importance to study tissue complexity, development, and physiology and has a vital role in understanding pathologies.
Matthijs J. D. Baars, Neeraj Sinha, Mojtaba Amini, Annelies Pieterman-Bos, Stephanie van Dam, Maroussia M. P. Ganpat, Miangela M. Laclé, Bas Oldenburg, Yvonne Vercoulen   +8 more
doaj   +1 more source

A Multimodal SIMS/MALDI Mass Spectrometry Imaging Source with Secondary Electron Imaging Capabilities for Use with timsTOF Instruments

, 2023
Mass spectrometry imaging (MSI) is a surface analysis technique that produces chemical images and is commonly used for biological and biomedical research.
Sebastian Böhm (14765814), Ian G. M. Anthony (5810702), Heeren, R.M.A., Kasper Krijnen (14765811), Hohndorf, J., Keelor, J.D., Anthony, I.G.M., Krijnen, K., Ron M. A. Heeren (7181636), Joel D. Keelor (1898416), Bohm, S., Koster, C., Shane R. Ellis (1862107), Claus Köster (14765817), Jens Höhndorf (8947847), Ellis, S.R.   +15 more
core   +1 more source

A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue

Frontiers in Immunology, 2020
Imaging mass cytometry (IMC) is able to quantify the expression of dozens of markers at sub-cellular resolution on a single tissue section by combining a novel laser ablation system with mass cytometry.
Nannan Guo, Vincent van Unen, Vincent van Unen, Marieke E. Ijsselsteijn, Laura F. Ouboter, Andrea E. van der Meulen, Susana M. Chuva de Sousa Lopes, Noel F. C. C. de Miranda, Frits Koning, Na Li, Na Li   +10 more
doaj   +1 more source