Results 11 to 20 of about 5,090,386 (280)

Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry [PDF]

Cell Systems, 2018
ISSN:2405 ...
Chevrier, Stéphane, Crowell, Helena L, Zanotelli, Vito R T, Engler, Stefanie, Robinson, Mark D, Bodenmiller, Bernd   +5 more
core   +7 more sources

An imaging mass cytometry immunophenotyping panel for non-human primate tissues [PDF]

Frontiers in Immunology, 2022
It has recently become clear that spatial organization contributes to cellular function and that expanding our knowledge on cellular organization is essential to further our understanding of processes in health and disease. Imaging mass cytometry enables
Paula Niewold, Marieke E. Ijsselsteijn, Frank A. W. Verreck, Tom H. M. Ottenhoff, Simone A. Joosten   +4 more
doaj   +2 more sources

Imaging mass cytometry reveals tissue-specific cellular immune phenotypes in the mouse knee following ACL injury [PDF]

Osteoarthritis and Cartilage Open, 2023
Objective: To develop an imaging mass cytometry method for identifying complex cell phenotypes, inter-cellular interactions, and population changes in the synovium and infrapatellar fat pad (IFP) of the mouse knee following a non-invasive compression ...
Sanique M. South, M. Caleb Marlin, Padmaja Mehta-D'souza, Tayte Stephens, Taylor Conner, Kevin G. Burt, Joel M. Guthridge, Carla R. Scanzello, Timothy M. Griffin   +8 more
doaj   +2 more sources

IMC-Denoise: a content aware denoising pipeline to enhance Imaging Mass Cytometry [PDF]

Nature Communications, 2023
Multiplexed imaging technologies can reveal the complex cellular and molecular profiles of tissue. Here, the authors develop and implement a denoising pipeline to significantly enhance imaging mass cytometry quality and improve single-cell analyses.
Peng Lu, Karolyn A. Oetjen, Diane E. Bender, Marianna B. Ruzinova, Daniel A. C. Fisher, Kevin G. Shim, Russell K. Pachynski, W. Nathaniel Brennen, Stephen T. Oh, Daniel C. Link, Daniel L. J. Thorek   +10 more
doaj   +2 more sources

High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture

Frontiers in Immunology, 2021
The integrative analysis of tumor immune microenvironment (TiME) components, their interactions and their microanatomical distribution is mandatory to better understand tumor progression.
Roxane Elaldi, Roxane Elaldi, Patrice Hemon, Luciana Petti, Estelle Cosson, Belinda Desrues, Anne Sudaka, Gilles Poissonnet, Ellen Van Obberghen-Schilling, Jacques-Olivier Pers, Veronique M. Braud, Fabienne Anjuère, Aïda Meghraoui-Kheddar   +12 more
doaj   +3 more sources

Imaging mass cytometry dataset of small-cell lung cancer tumors and tumor microenvironments [PDF]

BMC Research Notes
Objectives Small cell lung cancer (SCLC) accounts for approximately 15% of lung tumors and is marked by aggressive growth and early metastatic spread. In this study, we used two SCLC mouse models with differing tumor mutation burdens (TMB).
France Rose, Olta Ibruli, Luca Lichius, Martha Kiljan, Gokcen Gozum, Manoela Iannicelli Caiaffa, Jiali Cai, Li-na Niu, Jan M. Herter, Holger Grüll, Reinhard Büttner, Filippo Beleggia, Graziella Bosco, Julie George, Grit S. Herter-Sprie, Hans Christian Reinhardt, Katarzyna Bozek   +16 more
doaj   +2 more sources

From surfing to diving into the tumor microenvironment through multiparametric imaging mass cytometry [PDF]

Frontiers in Immunology
The tumor microenvironment (TME) is a complex ecosystem where malignant and non-malignant cells cooperate and interact determining cancer progression. Cell abundance, phenotype and localization within the TME vary over tumor development and in response ...
Marco Erreni, Marco Erreni, Maria Rita Fumagalli, Matteo Marozzi, Roberto Leone, Raffaella Parente, Raffaella D’Anna, Andrea Doni   +7 more
doaj   +2 more sources

Unveiling the immune landscape and microenvironmental architecture of IgA nephropathy using single‐cell imaging mass cytometry [PDF]

Clinical & Translational Immunology
Objective The heterogeneity in the pathology of IgA nephropathy (IgAN) represents a significant gap in current research, emphasising the need for individualised treatment strategies.
Xing Chen, Long Liu, Lijing Yao, Jianxin Shen, Hengyuan Zhang, Leping Shao, Xingxing Yu, Zhijuan Lin, Lu Zhang   +8 more
doaj   +2 more sources

High-resolution imaging mass cytometry to map subcellular structures. [PDF]

Nat Methods
Imaging mass cytometry (IMC) is a powerful multiplexed imaging technology used to investigate cell phenotypes and spatial organization of tissue in health and disease. The spatial resolution of IMC is presently at 1 µm, enabling the resolution of single cells and large subcellular compartments but not submicrometer intracellular structures.
Bollhagen A, Whipman J, Coelho R, Heinzelmann-Schwarz V, Jacob F, Bodenmiller B.   +5 more
europepmc   +3 more sources

Using Imaging Mass Cytometry to Define Cell Identities and Interactions in Human Tissues

Frontiers in Physiology, 2021
In the evolving landscape of highly multiplexed imaging techniques that can be applied to study complex cellular microenvironments, this review characterizes the use of imaging mass cytometry (IMC) to study the human kidney.
Vijayakumar R. Kakade, Marlene Weiss, Lloyd G. Cantley   +2 more
doaj   +3 more sources