Methods for analyzing tellurium imaging mass cytometry data.
PLoS ONE, 2019 Imaging mass cytometry (IMC) is a technique allowing visualization and quantification of over 40 biological parameters in a single experiment with subcellular spatial resolution, however most IMC experiments are limited to endpoint analysis with ...
Jay Bassan, Mark Nitz
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Imaging mass cytometry for high-dimensional tissue profiling in the eye [PDF]
BMC Ophthalmology, 2021 Background Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers unique advantages for the analysis of tissue samples in unprecedented detail.
Anja Schlecht +11 more
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Multidimensional profiling of drug‐treated cells by Imaging Mass Cytometry [PDF]
FEBS Open Bio, 2019 In pharmaceutical research, high‐content screening is an integral part of lead candidate development. Measuring drug response in vitro by examining over 40 parameters, including biomarkers, signaling molecules, cell morphological changes, proliferation ...
Alexandre Bouzekri +2 more
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Unveiling the immune landscape and microenvironmental architecture of IgA nephropathy using single-cell imaging mass cytometry. [PDF]
Clin Transl ImmunologyObjective The heterogeneity in the pathology of IgA nephropathy (IgAN) represents a significant gap in current research, emphasising the need for individualised treatment strategies.
Chen X +8 more
europepmc +2 more sources
Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach. [PDF]
Front ImmunolImaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting ...
Hemon P +7 more
europepmc +2 more sources
Different approaches to Imaging Mass Cytometry data analysis. [PDF]
Bioinform Adv, 2023 Summary Imaging Mass Cytometry (IMC) is a novel, high multiplexing imaging platform capable of simultaneously detecting and visualizing up to 40 different protein targets. It is a strong asset available for in-depth study of histology and pathophysiology of the tissues.
Milosevic V.
europepmc +5 more sources
Pan-cancer convergence of tumour-immune microenvironment motifs revealed by CyTOF and imaging mass cytometry. [PDF]
Front ImmunolVallée A, Drezet A, Arutkin M.
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Dice-XMBD: Deep Learning-Based Cell Segmentation for Imaging Mass Cytometry
Frontiers in Genetics, 2021 Highly multiplexed imaging technology is a powerful tool to facilitate understanding the composition and interactions of cells in tumor microenvironments at subcellular resolution, which is crucial for both basic research and clinical applications ...
Xu Xiao +11 more
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Flow Cytometry II: Mass and Imaging Cytometry [PDF]
Journal of Investigative Dermatology, 2015 Correction to: Journal of Investigative Dermatology (2015) 135, e36; doi:10.1038/id.2015 ...
Doan, Hung +2 more
openaire +3 more sources
Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research
Frontiers in Immunology, 2022 Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais +5 more
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