Results 71 to 80 of about 5,090,386 (280)

Maxpar Antibody Labeling for Imaging Mass Cytometry v1 [PDF]

, 2020
Version 11 of the antibody labelling protocol published by Fluidigm.
Marda Jorgensen, Michelle Daniel
openaire   +1 more source

The Composition of Poly(Ethylene Terephthalate) (PET) Surface Precipitates Determined at High Resolving Power by Tandem Mass Spectrometry Imaging [PDF]

, 2017
We present the first demonstration of a general method for the chemical characterization of small surface features at high magnification via simultaneous collection of mass spectrometry (MS) imaging and tandem MS imaging data.
Scott R. Bryan, Heeren, Ron M. A., Gregory L. Fisher, John S. Hammond, Bryan, Scott R., Larson, Paul E., Fisher, Gregory L., Hammond, John S., Paul E. Larson, Ron M. A. Heeren   +9 more
core   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A platinum polymer probe for multiplexed single cell suspension mass cytometry and imaging mass cytometry assays

Chemical Engineering Journal
Mitchell Winnik, Daniel Majonis
exaly   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome [PDF]

, 2017
Glycosylation in cancer is a highly dynamic process that has a significant impact on tumor biology. Further, the attachment of aberrant glycan forms is already considered a hallmark of the disease state.
Lordick, Florian, Kunzke, T., Axel Walch, Florian Lordick, Buck, Achim, Walch, A.K., Annette Feuchtinger, Langer, R., Achim Buck, Benjamin Balluff, Feuchtinger, A., Michaela Aichler, Balluff, Benjamin, Langer, Rupert, Walch, Axel, Kunzke, Thomas, Birgit Luber, Zitzelsberger, Horst, Luber, Birgit, Aichler, Michaela, Buck, A., Feuchtinger, Annette, Rupert Langer, Zitzelsberger, H., Balluff, B., Aichler, M., Luber, B., Thomas Kunzke, Lordick, F., Horst Zitzelsberger   +29 more
core   +2 more sources

Imaging mass cytometry data from breast cancer patient derived xenografts

, 2021
Imaging mass cytometry data from breast cancer patient derived ...
Maurizio Callari
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Single-cell mass cytometry in immunological skin diseases

Frontiers in Immunology
Immune-related skin diseases represent a collective of dermatological disorders intricately linked to dysfunctional immune system processes. These conditions are primarily characterized by an immoderate activation of the immune system or deviant immune ...
Mingming Zhao, Mingming Zhao, Mingming Zhao, Mingming Zhao, Yuqi Cheng, Yuqi Cheng, Yuqi Cheng, Yuqi Cheng, Jinping Gao, Jinping Gao, Jinping Gao, Jinping Gao, Fusheng Zhou, Fusheng Zhou, Fusheng Zhou, Fusheng Zhou   +15 more
doaj   +1 more source

Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

eLife, 2019
Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular content.
Valeria Ramaglia, Salma Sheikh-Mohamed, Karen Legg, Calvin Park, Olga L Rojas, Stephanie Zandee, Fred Fu, Olga Ornatsky, Eric C Swanson, David Pitt, Alexandre Prat, Trevor D McKee, Jennifer L Gommerman   +12 more
doaj   +1 more source