Results 11 to 20 of about 779,870 (354)

STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau   +14 more
doaj   +1 more source

Analysis of the differentiation of peripheral B-lymphocytes in pregnant women with a habitual miscarriage

Сибирский научный медицинский журнал, 2021
The frequency of recurrent miscarriage among all desired pregnancies is 2-5 %. The important role of immune disorders in early termination of pregnancy has been proven.
N. Yu. Sotnikova, A. I. Malyshkina, A. V. Kust, D. N. Voronin   +3 more
doaj   +1 more source

Simulated patient and role play methodologies for communication skills and empathy training of undergraduate medical students

BMC Medical Education, 2020
Background Verbal and non-verbal communication, as well as empathy are central to patient-doctor interactions and have been associated with patients’ satisfaction. Non-verbal communication tends to override verbal messages.
Cristina Bagacean, Ianis Cousin, Anne-Helene Ubertini, Mohamed El Yacoubi El Idrissi, Anne Bordron, Lolita Mercadie, Leonor Canales Garcia, Jean-Christophe Ianotto, Philine De Vries, Christian Berthou   +9 more
doaj   +1 more source

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N, Coombs, Andrew J, Dellaire, Graham, Druley, Todd E, Ha, Michael N, McCormick, Craig, Melong, Nicole, O\u27Leary, David, Pringle, Eric S, Robinson, Carolyn-Ann, Veinotte, Chansey, Wertman, Jaime, Young, Andrew L   +12 more
core   +2 more sources

B Lymphocytes in Parkinson’s Disease

Journal of Parkinson’s Disease, 2022
It is well known that B lymphocytes differentiate into plasma cells that produce antibodies. B cells also perform a number of less well-known roles including antigen presentation, regulation of T cells and innate immune cells, cytokine production, and ...
Kirsten M. Scott
doaj   +1 more source

Combining cytogenetic and epigenetic approaches in chronic lymphocytic leukemia improves prognosis prediction for patients with isolated 13q deletion

Clinical Epigenetics, 2017
Background Both defective DNA methylation and active DNA demethylation processes are emerging as important risk factors in chronic lymphocytic leukemia (CLL).
Cristina Bagacean, Christelle Le Dantec, Christian Berthou, Adrian Tempescul, Hussam Saad, Anne Bordron, Mihnea Zdrenghea, Victor Cristea, Nathalie Douet-Guilbert, Yves Renaudineau   +9 more
doaj   +1 more source

IMMUNOLOGICAL AND PATHOMORPHOLOGICAL ASPECTS OF EARLY AND LATE PREECLAMPSIA

Медицинская иммунология, 2021
Preeclampsia (PE) is one of the most common complications of pregnancy, and it can be after 20 weeks of gestation. It ends only with a complete dissection of afterbirth. Traditionally, PE is subdivided into the early one, taking place through 34 weeks of
A. S. Panaschatenko, I. A. Panova, A. I. Malyshkina, E. A. Rokotyanskaya, A. V. Kudryashova, N. Yu. Sotnikova, L. V. Kulida, E. V. Protsenko   +7 more
doaj   +1 more source

Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]

, 1987
Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
Denis, KA, Dorshkind, K, Witte, ON
core   +2 more sources

Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis. [PDF]

, 1988
In patients with rheumatoid arthritis (RA), circulating CD5+ B lymphocytes, but not CD5- B lymphocytes, are increased in number and size, exist in an activated state, spontaneously proliferate, and secrete Ig that binds to the Fc fragment of IgG.
Burastero, SE, Casali, P, Notkins, AL, Wilder, RL   +3 more
core   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source