Results 21 to 30 of about 13,971,057 (260)

Analysis of the differentiation of peripheral B-lymphocytes in pregnant women with a habitual miscarriage

Сибирский научный медицинский журнал, 2021
The frequency of recurrent miscarriage among all desired pregnancies is 2-5 %. The important role of immune disorders in early termination of pregnancy has been proven.
N. Yu. Sotnikova, A. I. Malyshkina, A. V. Kust, D. N. Voronin   +3 more
doaj   +1 more source

Combining cytogenetic and epigenetic approaches in chronic lymphocytic leukemia improves prognosis prediction for patients with isolated 13q deletion

Clinical Epigenetics, 2017
Background Both defective DNA methylation and active DNA demethylation processes are emerging as important risk factors in chronic lymphocytic leukemia (CLL).
Cristina Bagacean, Christelle Le Dantec, Christian Berthou, Adrian Tempescul, Hussam Saad, Anne Bordron, Mihnea Zdrenghea, Victor Cristea, Nathalie Douet-Guilbert, Yves Renaudineau   +9 more
doaj   +1 more source

IMMUNOLOGICAL AND PATHOMORPHOLOGICAL ASPECTS OF EARLY AND LATE PREECLAMPSIA

Медицинская иммунология, 2021
Preeclampsia (PE) is one of the most common complications of pregnancy, and it can be after 20 weeks of gestation. It ends only with a complete dissection of afterbirth. Traditionally, PE is subdivided into the early one, taking place through 34 weeks of
A. S. Panaschatenko, I. A. Panova, A. I. Malyshkina, E. A. Rokotyanskaya, A. V. Kudryashova, N. Yu. Sotnikova, L. V. Kulida, E. V. Protsenko   +7 more
doaj   +1 more source

Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]

, 2013
Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M, Cerutti, A, Andrea Cerutti, Puga, I, Montserrat Cols, Irene Puga   +5 more
core   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

Inflammation is responsible for systemic bone loss in patients with seropositive rheumatoid arthritis treated with rituximab [PDF]

The Korean Journal of Internal Medicine, 2023
Background/Aims We investigated the effect of rituximab on systemic bone metabolism in patients with seropositive rheumatoid arthritis (RA). Methods Twenty seropositive patients with RA were enrolled and administered one cycle of rituximab.
Mie Jin Lim, Kyong-Hee Jung, Seong-Ryul Kwon, Won Park   +3 more
doaj   +1 more source

Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes. [PDF]

, 2016
Cardiolipin (CL) is an inner mitochondrial membrane phospholipid which plays an important role in mitochondrial function. Perturbation in CL biosynthesis alters mitochondrial bioenergetics causing a severe genetic disorder commonly known as Barth ...
V Ashutosh Rao, Baikuntha Aryal (441940), Baikuntha Aryal, V. Ashutosh Rao (441950)   +3 more
core   +1 more source

17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean, Adrian Tempescul, David Ternant, Anne Banet, Nathalie Douet-Guilbert, Anne Bordron, Boutahar Bendaoud, Hussam Saad, Mihnea Zdrenghea, Christian Berthou, Gilles Paintaud, Yves Renaudineau   +11 more
doaj   +1 more source

JAK Inhibitors and Oxidative Stress Control

Frontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras, Pinelopi Arvaniti, Pinelopi Arvaniti, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, George N. Dalekos, Kaliopi Zachou, Kaliopi Zachou, Anne Bordron, Yves Renaudineau, Yves Renaudineau   +11 more
doaj   +1 more source

B Lymphocytes in Parkinson’s Disease

Journal of Parkinson’s Disease, 2022
It is well known that B lymphocytes differentiate into plasma cells that produce antibodies. B cells also perform a number of less well-known roles including antigen presentation, regulation of T cells and innate immune cells, cytokine production, and ...
Kirsten M. Scott
doaj   +1 more source