Results 21 to 30 of about 693,632 (262)
Zhongliu Fangzhi Yanjiu, 2021 Objective To explore the correlation between EBV DNA load and peripheral immune cells (including lymphocyte supsets and natural killer cells) before treatment in patients with NPC, and analyze the influence of circulating immune cell supsets related to ...
WEI Xueling +6 more
doaj +1 more source
CD4+ T cells reverse surface antigen persistence in a mouse model of HBV replication
Microbiology Spectrum, 2023 Hepatitis B virus (HBV) is responsible for over 800,000 deaths yearly worldwide. While chronic HBV infection currently has no highly effective cure, immunotherapy has generated interest as a potential therapeutic solution due to the connection between ...
Jacob T. Bailey +4 more
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Experimental Biology and Medicine, 1991 SummaryA major proportion of CD5+ B lymphocytes are committed to the production of a discrete type of antibody that is polyreactive. Polyreactive antibodies appear to use selected V and, perhaps, D gene segments, mostly in unmutated configuration. They generally display relatively low affinity for different antigens and are often part of the primary ...
M T, Kasaian, H, Ikematsu, P, Casali
openaire +2 more sources
Arthritis Research & Therapy, 2017 Background The objective was to evaluate concordance between 2002 American-European Consensus Group (AECG) and 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for primary Sjögren’s syndrome ...
Maëlle Le Goff +13 more
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Japanese Journal of Clinical Immunology, 2005 Recent studies have revealed that B cells play a critical role in autoimmunity and disease expression through various functions, including autoantibody production, cytokine secretion, antigen presentation, and co-stimulatory effect. Selective targeting of B cells has been recently achieved using a chimeric monoclonal antibody against CD20 (Rituximab ...
openaire +3 more sources
Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach
Frontiers in ImmunologyImaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting ...
Patrice Hemon +11 more
doaj +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Бюллетень сибирской медицины, 2010 Alternatively spliced interleukins are very actively studied over the last years. Splice form of IL-4 — IL-4δ2 has antagonistic effects to its full form on proliferative activity of human mononuclear blood cells and their IL-6 production.
K. V. Goremykin +5 more
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Case Reports in Nephrology and Dialysis, 2022 Studies investigating the effect of rituximab in children with nephrotic syndrome (NS) due to focal segmental glomerulosclerosis (FSGS) have reported conflicting results, with some concluding that patients may require additional immunosuppressive therapy
Cahyani Gita Ambarsari +2 more
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