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Inflammation is responsible for systemic bone loss in patients with seropositive rheumatoid arthritis treated with rituximab [PDF]
The Korean Journal of Internal Medicine, 2023 Background/Aims We investigated the effect of rituximab on systemic bone metabolism in patients with seropositive rheumatoid arthritis (RA). Methods Twenty seropositive patients with RA were enrolled and administered one cycle of rituximab.
Mie Jin Lim +3 more
doaj +1 more source
Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]
, 1986 Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van +4 more
core +4 more sources
Experimental Biology and Medicine, 1991 SummaryA major proportion of CD5+ B lymphocytes are committed to the production of a discrete type of antibody that is polyreactive. Polyreactive antibodies appear to use selected V and, perhaps, D gene segments, mostly in unmutated configuration. They generally display relatively low affinity for different antigens and are often part of the primary ...
M T, Kasaian, H, Ikematsu, P, Casali
openaire +2 more sources
17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia
Journal for ImmunoTherapy of Cancer, 2019 Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean +11 more
doaj +1 more source
Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]
, 1974 T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core +1 more source
JAK Inhibitors and Oxidative Stress Control
Frontiers in Immunology, 2019 Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras +11 more
doaj +1 more source
Avicenna Journal of Medicine, 2020 Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem +6 more
doaj +1 more source
Classical scrapie prions in ovine blood are associated with B lymphocytes and platelet-rich plasma [PDF]
, 2011 Background Classical scrapie is a naturally occurring transmissible spongiform encephalopathy of sheep and goats characterized by cellular accumulation of abnormal isoforms of prion protein (PrPSc) in the central nervous system and the follicles of ...
Rohana P Dassanayake +5 more
core +1 more source
CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION
Siberian Journal of Life Sciences and Agriculture, 2023 The article presents the results of the analysis of clinical and morphological characteristics and a number of indicators of peripheral blood in children with a new coronavirus infection.
Elizaveta S. Ageeva +6 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2021 Objective To explore the correlation between EBV DNA load and peripheral immune cells (including lymphocyte supsets and natural killer cells) before treatment in patients with NPC, and analyze the influence of circulating immune cell supsets related to ...
WEI Xueling +6 more
doaj +1 more source