Results 191 to 200 of about 2,138,197 (387)

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

Nature Medicine, 2015
W. Wilson, R. Young, R. Schmitz, Yandan Yang, S. Pittaluga, George W. Wright, C. Lih, P. Williams, A. Shaffer, J. Gerecitano, J. Gerecitano, S. Vos, A. Goy, V. Kenkre, P. Barr, K. Blum, A. Shustov, R. Advani, N. Fowler, J. Vose, R. Elstrom, T. Habermann, J. Barrientos, J. Mcgreivy, M. Fardis, B. Chang, F. Clow, B. Munneke, D. Moussa, D. Beaupre, L. Staudt   +30 more
semanticscholar   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Adhesion molecule profiles of B-cell non-Hodgkin's lymphomas in the leukemic phase

Brazilian Journal of Medical and Biological Research, 2006
We evaluated the expression of 10 adhesion molecules on peripheral blood tumor cells of 17 patients with chronic lymphocytic leukemia, 17 with mantle-cell lymphoma, and 13 with nodal or splenic marginal B-cell lymphoma, all in the leukemic phase and ...
D.M. Matos, E.G. Rizzatti, A.B. Garcia, D.A.P. Gallo, R.P. Falcão   +4 more
doaj  

A Case Report of Diffuse Large B-cell Lymphoma Masquerading as Necrotizing Lymph Nodes: The Role of Core Needle Biopsy for Early Diagnosis

, 2018
Hamed Emami, Shayan Abdollah Zadegan, Hirbod Nasiri Bonaki, Reza Erfanian   +3 more
openalex   +1 more source

Additional file 1 of Clinical implications of circulating tumor DNA in predicting the outcome of diffuse large B cell lymphoma patients receiving first-line therapy

, 2022
Miaomiao Li, Lan Mi, Chunyang Wang, Xiaojuan Wang, Jianhua Zhu, Fei Qi, Hui Yu, Yingying Ye, Dedao Wang, Jiaowu Cao, Dingyao Hu, Quanyu Yang, Dandan Zhao, Tonghui Ma, Yuqin Song, Jun Zhu   +15 more
openalex   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

T-cell rich B-cell large cell lymphoma.

, 1991
Soji Kurita, Shigeo Nakamura, Takashi Koshikawa, Kiyoko FUSE, Keiko Nakazato, Etsuko Kato, Sadayuki Kaba, Katsuko OKUDA, Taizan Suchi   +8 more
openalex   +2 more sources

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

Nature, 2010
R. Davis, V. Ngo, G. Lenz, P. Tolar, R. Young, Paul B. Romesser, H. Kohlhammer, L. Lamy, Hong Zhao, Yandan Yang, Weihong Xu, A. Shaffer, George W. Wright, Wenming Xiao, J. Powell, Jian-Kang Jiang, Craig J. Thomas, A. Rosenwald, G. Ott, H. Müller-hermelink, R. Gascoyne, J. Connors, N. Johnson, L. Rimsza, E. Campo, E. Jaffe, W. Wilson, J. Delabie, E. Smeland, R. Fisher, R. Braziel, R. Tubbs, J. Cook, D. Weisenburger, W. C. Chan, S. Pierce, L. Staudt   +36 more
semanticscholar   +1 more source

The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma.

Cancer Cell, 2021
C. Steen, Bogdan Luca, M. S. Esfahani, Armon Azizi, B. Sworder, B. Nabet, D. Kurtz, C. Liu, Farnaz Khameneh, R. Advani, Y. Natkunam, J. Myklebust, M. Diehn, A. Gentles, Aaron M. Newman, A. Alizadeh   +15 more
semanticscholar   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source