Results 191 to 200 of about 21,159,025 (295)

Diffuse Nephromegaly With Dialysis-Dependent Acute Kidney Injury as the Initial Presentation of Primary Mediastinal Large B-Cell Lymphoma. [PDF]

Case Rep Nephrol
Khor ZX.
europepmc   +1 more source

Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA 2020 flow diagram of included studies. ABSTRACT Purpose Immune checkpoint inhibitors have transformed treatment strategies for metastatic non‐small cell lung cancer (mNSCLC). This study aimed to assess the efficacy and safety of durvalumab combined with tremelimumab compared with those of standard chemotherapy, particularly in patients with low ...
Ikhwan Rinaldi, Eric Ricardo Yonatan, Tasia Esterita   +2 more
wiley   +1 more source

Telemedicine-Guided Pericardiocentesis for Cardiac Tamponade in Primary Mediastinal Large B-cell Lymphoma. [PDF]

Cureus
Cab Morales VA, Montemayor Garza EA, Mascorro-Cienfuegos CA, Aguilar-Meza JL, de la Cruz de León NA, Chavarría Martínez U.   +5 more
europepmc   +1 more source

Multimodal Imaging of Live Cells and Tumor Spheroids by a G‐Quadruplex DNA Selective Ru(II)Polypyridyl Probe

Chemistry – A European Journal, EarlyView.
Harnessing the light‑switch properties of Ru‑PDC3, we demonstrate that it binds to G‑quadruplex DNA within the nuclei of living cells where it can act as a probe for real‑time imaging or at higher concentrations/illumination it can act as photosensitizer inducing phototoxicity.
Karmel S. Gkika, Lorcan Holden, Giuseppe Avella, Rhianne C. Curley, Nirod K. Sarangi, Tia E. Keyes   +5 more
wiley   +1 more source

Editorial: Mechanisms regulating immune evasion by B-cell lymphoma. [PDF]

Front Immunol
Muniraj N, Haque A.
europepmc   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Oncogenic Mutations and Tumor Microenvironment Alterations in Diffuse Large B-Cell Lymphoma With Bulky Disease. [PDF]

Cancer Med
Wang YQ, Wang Y, Du ZS, Huang XY, Dong Y, Tian S, Fu D, Cheng S, Wang L, Xu PP, Fan SJ, Wang SY.   +11 more
europepmc   +1 more source

Risk of Bias Associated with Varying Sampling Strategies for External Comparator Cohorts for Single‐Arm Trials: Insights from Aggressive Lymphoma

Clinical Pharmacology &Therapeutics, EarlyView.
Marketing authorizations for oncology drugs are often based on single‐arm trials (SATs), and real‐world data‐based external comparator cohorts (ECCs) are increasingly explored to contextualize results. In retrospective studies, comparators may be identified by time of diagnosis but included based on time of relapse; such sampling strategies can ...
Mikkel Runason Simonsen, Shiva Leisner, Ahmed Ludvigsen Al‐Mashhadi, Laurids Østergaard Poulsen, Matthew Maurer, Lasse Hjort Jakobsen, Tarec Christoffer El‐Galaly   +6 more
wiley   +1 more source

Establishment of Patient-Derived Xenotransplant and Cell Line Models for Canine B-Cell Lymphoma. [PDF]

Cells
Leung W, Pierpont TM, Webb S, Hayward JJ, Markant S, Belcher N, Butler SD, Puri R, Byron MJ, Castelhano MG, Inghirami G, Miller AD, Stokol T, Richards KL, McCleary-Wheeler AL, Weiss RS.   +15 more
europepmc   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source