Results 91 to 100 of about 12,730,863 (301)

A Case of B-Cell Lymphoblastic Lymphoma Presenting with an Isolated Epidural Mass Treated Successfully with Radiotherapy Followed by United Kingdom Acute Lymphoblastic Leukemia (UKALL) Chemotherapy Protocol

Hematology Reports
Background: B-cell lymphoblastic lymphoma (B-LBL) is an aggressive type of non-Hodgkin lymphoma that usually involves lymph nodes, skin and soft tissue. Bone marrow and peripheral blood are normally spared from involvement in the disease. B-LBL typically
Musa Fares Alzahrani
doaj   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

MicroRNA profiling in B cell non-Hodgkin Lymphoma : focus on the role of MYC [PDF]

, 2013
Non-Hodgkinlymfoon is een kwaadaardige vorm van kanker die uitgaat van de lymfeklieren. De ziekte wordt gekenmerkt door specifieke chromosoomafwijkingen en door afwijkende patronen van genexpressie.
Robertus, Jan Lukas,, Robertus, Jan Lukas   +1 more
core   +1 more source

B-lymphoblastic leukemia/lymphoma arising in treated plasma cell myeloma: A rare second malignancy

Human Pathology: Case Reports, 2017
Plasma cell myeloma (PCM) is a neoplasm of plasma cells, end-stage post germinal center B cells, which shows a variable clinical spectrum from asymptomatic to aggressive; the nature of the disease is generally progressive. Rarely, leukemia arises treated
D. Kurant, S.I. Fisher, W. Tang, N.S. Aguilera   +3 more
doaj   +1 more source

Germline deletion of ETV6 in familial acute lymphoblastic leukemia.

Blood Advances, 2019
Recent studies have identified germline mutations in TP53, PAX5, ETV6, and IKZF1 in kindreds with familial acute lymphoblastic leukemia (ALL), but the genetic basis of ALL in many kindreds is unknown despite mutational analysis of the exome.
E. Rampersaud, David S. Ziegler, I. Iacobucci, D. Payne-Turner, Michelle L. Churchman, K. Schrader, V. Joseph, K. Offit, K. Tucker, R. Sutton, M. Warby, G. Chenevix-Trench, D. Huntsman, M. Tsoli, R. S. Mead, Chunxu Qu, Vasiliki Leventaki, Gang Wu, C. Mullighan   +18 more
semanticscholar   +1 more source

Primary Dural Lymphoblastic B-Cell Lymphoma: A Rare Subtype of Aggressive Dural Lymphoma. [PDF]

, 2015
Lymphomas arising in the dura mater represent a rare subset of primary central nervous system lymphoma (PCNSL). The majority of primary dural lymphoma (PDL) are low-grade marginal zone lymphomas (MZL) characterized by an indolent course and favorable ...
Saraceni, Christine, Gheith, Shereen M F, Agostino, Nicole M, DO, Gheith, Shereen M, MD   +3 more
core   +1 more source

Bortezomib‐based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single‐center retrospective study

Pediatric Investigation, EarlyView.
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao, Jian Wang, Liping Que, Dunhua Zhou, Jianpei Fang, Luhong Xu   +5 more
wiley   +1 more source

AIDS and Non AIDS-Related Malignant Lymphoma in Tanzania. [PDF]

, 2006
Malignant lymphoma (ML) in HIV patients, are second in frequency to Kaposi's sarcoma (AKS) as AIDS-defining tumors. In Africa the frequency of AIDS-related lymphoma (ARL) is rare and the findings are controversial.
Ekman, Marianne, Lema, Leonard, Biberfeld, P., Kitinya, J, Carneiro, P, Kitinya, James, Kaaya, EE, Kaaya, Ephata E, Biberfeld, P, Linde, A., Castaños-Velez, E, Lema, L, Carneiro, Primo, Lema, L., Kaaya, E.E., Mwakigonja, A., Biberfeld, Peter, Mwakigonja, A, Carneiro, P., Castaños-Velez, Esmeralda, Mwakigonja, Amos, Ekman, M, Linde, Anika, Castaños-Velez, E., Ekman, M., Linde, A   +25 more
core   +1 more source

The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models

Haematologica, 2019
Antibody-drug conjugates (ADC) are a novel way to deliver potent cytotoxic compounds to cells expressing a specific antigen. Four ADC targeting CD19, including SAR3419 (coltuximab ravtansine), have entered clinical development.
S. Hicks, C. Tarantelli, A. Wilhem, E. Gaudio, Min Li, A. Arribas, F. Spriano, R. Bordone, L. Cascione, Katharine C. Lai, Qifeng Qiu, M. Taborelli, D. Rossi, G. Stussi, E. Zucca, A. Stathis, C. Sloss, F. Bertoni   +17 more
semanticscholar   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source