Results 211 to 220 of about 451,514 (257)

scCCVGBen for benchmarking of single-cell representation learning anchored on a centroid-coupled variational graph attention autoencoder across scRNA-seq and scATAC-seq. [PDF]

Front Genet
Fu Z, Fu J, Chen C, Zhang K, Wang J, Ran T, Wang S.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Tracing aesthetic experience from perception and conception to appraisal using deep convolutional neural networks. [PDF]

iScience
Lin Y, Verlinde L, Wagemans J, Op de Beeck H.   +3 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The failure of the Ehlers-Kundt conjecture in the impulsive case. [PDF]

Gen Relativ Gravit
Frauenberger ML, Grant JDE, Steinbauer R.   +2 more
europepmc   +1 more source

Diverse Microbial Communities Assemble on Both Recalcitrant and Labile Carbon Sources. [PDF]

Environ Microbiol
Prabhakara KH, Zhao Y, Ullrich K, Farr AD, Rainey PB.   +4 more
europepmc   +1 more source

Metric dimension of cycloparaphenylene and its derived molecular structures. [PDF]

Sci Rep
Prabhu S, Jeba DSR, Arulperumjothi M, Manuel P.   +3 more
europepmc   +1 more source

Ethnic-racial identity in Sweden: Dimensionality, measurement invariance, and psychosocial adjustment. [PDF]

J Res Adolesc
Reinholdsson T, Frisén A, Hwang CP, Juang L, Stern PD, Syed M.   +5 more
europepmc   +1 more source

Measurement Equivalence of Diabetes Self-Management, Distress, and Quality-of-Life Measures in Adults with Type 2 Diabetes in Vietnam. [PDF]

Nurs Rep
Nguyen TT, Vo HT, Nguyen TTV, Son PM, Xim VT, Pham TMN, Phan MA, Nguyen TA.   +7 more
europepmc   +1 more source