Results 61 to 70 of about 41,355 (258)
Fixed Point Results for Cirić and Almost Contractions in Convex b-Metric Spaces
Mathematics, 2022 We establish a fixed point theorem for Cirić contraction in the context of convex b-metric spaces. Furthermore, we ensure that there is a fixed point for the maps satisfying the condition (B) (a kind of almost contraction) in convex b-metric spaces and ...
Savita Rathee +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
S∗p‐b-Partial Metric Spaces with some Results in Common Fixed Point Theorems
Journal of Function Spaces, 2021 In this paper, we introduce the notion of S∗P‐b-partial metric spaces which is a generalization each of S‐b-metric spaces and partial-metric space. Also, we study and prove some topological properties, to know the convergence of the sequences and Cauchy ...
A. M. Zidan
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Multivalued Contraction Fixed-Point Theorem in b-Metric Spaces
MathematicsThe authors explore fixed-point theory in b-metric spaces and strong b-metric spaces. They wish to prove some new extensions of the Covitz and Nadler fixed-point theorem in b-metric spaces. In so doing, they wish to answer a question proposed by Kirk and
Bachir Slimani +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Admissible Hybrid Z-Contractions in b-Metric Spaces [PDF]
Axioms, 2019 In this manuscript, we introduce a new notion, admissible hybrid Z -contraction that unifies several nonlinear and linear contractions in the set-up of a b-metric space. In our main theorem, we discuss the existence and uniqueness result of such mappings in the context of complete b-metric space.
Ioan Cristian Chifu, Erdal Karapinar
openaire +2 more sources
A New Variant of Symmetric Distance Spaces and an Extension of the Banach Fixed-Point Theorem
Journal of Mathematics, 2022 The notion of Δ-metric spaces has been proposed in this study as a generalization of b-metric spaces, extended b-metric spaces, and p-metric spaces. A number of topological characteristics of such spaces have been investigated in this paper.
Kushal Roy +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source