Results 131 to 140 of about 5,411,122 (304)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Dizhen xuebao使用云南地震台网2009—2021年的地震目录和波形数据，采用双差定位方法、基于P波初动极性和S/P振幅比的HASH方法和最大似然法等，获取了维西—乔后断裂带及附近地区ML≥4.0震群和前震序列精确的震源位置、震源机制解、视应力和b值等地震活动参数，对比分析了维西—乔后断裂带及其周边震群及前震序列的活动特征。结果显示：除前震序列频次呈现出反大森定律外，前震序列与普通震群在空间分布、震源机制一致性、视应力和b值等单一参数方面并无明显的差异；但前震序列同时具备震中优势分布方向与区域主要构造展布方向一致 ...
Guangming Wang +4 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Diffusion tensor imaging and fiber tractography of the median nerve at 1.5T: optimization of b value [PDF]
, 2018 Objective: The objective of this study was to systematically assess the optimal b value for diffusion tensor imaging and fiber tractography of the median nerve at 1.5T.
Andreisek, Gustav +4 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
General theory of the modified Gutenberg-Richter law for large seismic moments
, 1999 The Gutenberg-Richter power law distribution of earthquake sizes is one of the most famous example illustrating self-similarity. It is well-known that the Gutenberg-Richter distribution has to be modified for large seismic moments, due to energy ...
Sornette, A., Sornette, D.
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Sh(B)-Valued Models of $$(\kappa ,\kappa )$$-Coherent Categories
Applied Categorical StructuresAbstract A basic technique in model theory is to name the elements of a model by introducing new constant symbols. We describe the analogous construction in the language of syntactic categories/sites. As an application we identify $$\textbf{Set}$$ Set
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source