Results 41 to 50 of about 12,189,223 (218)

CCL20 and Beta-Defensin 2 Production by Human Lung Epithelial Cells and Macrophages in Response to Brucella abortus Infection.

PLoS ONE, 2015
Both CCL20 and human β-defensin 2 (hBD2) interact with the same membrane receptor and display chemotactic and antimicrobial activities. They are produced by airway epithelia in response to infectious agents and proinflammatory cytokines. Whereas Brucella
M Soledad Hielpos, Mariana C Ferrero, Andrea G Fernández, Josefina Bonetto, Guillermo H Giambartolomei, Carlos A Fossati, Pablo C Baldi   +6 more
doaj   +1 more source

B Lymphocytes Provide an Infection Niche for Intracellular Bacterium Brucella abortus [PDF]

The Journal of Infectious Diseases, 2012
Brucella spp. are intracellular bacteria that establish lifelong infections whose mechanisms of chronicity are poorly understood. Notably, B cells facilitate the establishment of the high infection plateau that persists for months.We evaluated the contribution of murine B cells toward providing infection niches for Brucella by using flow cytometry and ...
Radhika, Goenka, Patrick D, Guirnalda, Samuel J, Black, Cynthia L, Baldwin   +3 more
openaire   +2 more sources

Animal models of anemia of inflammation: Methodological advances, limitations, and translational applications

Animal Models and Experimental Medicine, EarlyView.
Anemia of inflammation is a highly prevalent secondary anemia complicating chronic inflammatory diseases. Current animal models are categorized into sterile inflammation, disease‐specific, and genetically engineered models, with comparative analysis of their modeling principles, characteristic phenotypes, and translational advantages to elucidate core ...
Jiayi Cheng, Xiaodi Zhou, Qian Liu, Zixian Liu, Hao Wu   +4 more
wiley   +1 more source

Adaptation mechanisms of Brucella abortus to low magnesium ion stress

BMC Veterinary Research
Background Brucella abortus, a facultative intracellular pathogenic bacterium that usually causes diseases under animals and humans, can survive and replicate within phagocytic cells. Within the host cells, B.
Hengtai Wang, Lang Lv, Yike Huang, Hui Jiang, Xiaowen Yang, Jiabo Ding, Liangquan Zhu, Lei Xu, Huaiming Sang, Jianxia Jiang, Nan Wang, Peng Li   +11 more
doaj   +1 more source

Phylogeny of Brucella abortus strains isolated in the Russian Federation

Asian Pacific Journal of Tropical Medicine, 2021
Objective: To study Brucella (B.) abortus strains isolated in the Russian Federation, in order to identify their detailed position in the phylogenetic structure of the species global population as well as to determine genetic relationships for isolates ...
Dmitry A Kovalev, Dmitriy G Ponomarenko, Sergey V Pisarenko, Nikolay A Shapakov, Anna A Khachaturova, Natalia S Serdyuk, Olga V Bobrysheva, Alexander N Kulichenko   +7 more
doaj   +1 more source

Culture‐Negative Infective Endocarditis Presumed due to Brucella Causing Rapid Native Aortic Valve Destruction in a Young Adult: A Case Report [PDF]

Clin Case Rep
ABSTRACT Culture‐negative endocarditis with features consistent with Brucella can rapidly destroy a normal aortic valve in young adults. 2023 Duke‐ISCVID criteria (clinical/imaging findings plus histopathology), supported by serology and occupational exposure enabled urgent combined antimicrobial‐surgical management without culture confirmation ...
Nassar B, Gharo K, Ramahi O, Ghannam H, Romana A, Hashhash K.   +5 more
europepmc   +2 more sources

Proteomic Analysis of Membrane Blebs of Brucella abortus 2308 and RB51 and Their Evaluation as an Acellular Vaccine

Frontiers in Microbiology, 2019
Membrane blebs are released from Gram-negative bacteria, however, little is known about Brucella blebs. This work pursued two objectives, the first was to determine and identify the proteins in the membrane blebs by proteomics and in silico analysis. The
Minerva Araiza-Villanueva, Eric Daniel Avila-Calderón, Eric Daniel Avila-Calderón, Leopoldo Flores-Romo, Juana Calderón-Amador, Nammalwar Sriranganathan, Hamzeh Al Qublan, Sharon Witonsky, Sharon Witonsky, Ma. Guadalupe Aguilera-Arreola, María del Socorro Ruiz-Palma, María del Socorro Ruiz-Palma, Enrico A. Ruiz, Francisco Suárez-Güemes, Zulema Gómez-Lunar, Araceli Contreras-Rodríguez   +15 more
doaj   +1 more source

Co‐Infection of Brucella canis and Brucella melitensis in a Domestic Dog With Zoonotic Transmission to Human, China

Animal Research and One Health, EarlyView.
Source attribution figure for human and dogs Brucella canis infections. ABSTRACT We report a rare occurrence of genetic material from both Brucella canis and B. melitensis detected in a domesticated dog from Jiangsu Province, China. The detection was confirmed through serological assays, quantitative PCR (qPCR), metagenomic and genomic sequencing ...
Shengxin Ge, Jian Xu, Qingchun Shen, Jiabo Ding, Xiaowen Yang   +4 more
wiley   +1 more source

Isolation, Identification and Molecular Characterization of Brucella abortus from Bovines

, 2017
Brucellosis is an important zoonosis and a significant cause of reproductive losses in animals. Abortion, placentitis, epididymitis and orchitis are the most common clinical manifestations in animals.
MD Shrimali, A.I. Dadawala, MA Patel, BS Chandel, JD Shah, N.M. Shah, JK Kala, M.A. Patel, A.G. Bhagat, B.S. Chandel, A.C. Patel, J.K. Kala, R.P. Pandya, K.B. Patel, Manish Rajgor, AG Bhagat, AI Dadawala, MG Patel, J.D. Shah, KB Patel, BK Patel, NM Shah, HC Chauhan, S.I. Patel, S.S. Patel, RP Pandya, AC Patel, H.C. Chauhan, M.D. Shrimali, M.G. Patel, SI Patel, B.K. Patel, SS Patel   +32 more
core   +1 more source

Host Interferon-Gamma Inducible Protein Contributes to Brucella Survival

Frontiers in Cellular and Infection Microbiology, 2012
Brucella spp. are highly adapted intracellular pathogens of mammals that cause chronic infections while surving and replicating in host monocytes and macrophages.
Jennifer eRitchie, Adam eRupper, James eCardelli, Bryan eBellaire   +3 more
doaj   +1 more source