Results 61 to 70 of about 20,137,358 (280)

Jacobsen and Skinner

, 2004
Publicity postcard for Mikel Jacobsen and Skid Skinner (Hector Skinner) showing them riding the Wall of ...
Skinner, Alma
core  

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Notas sobre a dicotomia “inato” versus “aprendido”

Interação em Psicologia, 2001
The literature that concentrates on the debate surrounding “innate” versus “learnt” in the determination of the behavioural phenomenon is often paradoxical: whilst stating that there is an unequivocal interaction between “biological” and “environmental ...
Marcus Bentes de Carvalho Neto, Emmanuel Zagury Tourinho   +1 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Comportamento aleatório: algumas considerações

Psicologia: Teoria e Pesquisa
Este estudo defende que o comportamento aleatório pode tornar-se legítimo objeto de estudo de uma ciência do comportamento. Analisamos inicialmente algumas considerações que B. F.
Lourenço de Souza Barba
doaj   +1 more source

A influência de eventos antecedentes nos problemas de comportamento infantil: revisão de conceitos e aplicabilidade

Interação em Psicologia, 2011
Considerando o aumento no número de estudos aplicados realizados no exterior e a ausência de publicações brasileiras em Análise do Comportamento que relacionam eventos antecedentes a problemas comportamentais infantis, este artigo objetiva descrever: (1)
Camila Carmo de Menezes, Márcia Cristina Caserta Gon   +1 more
doaj   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Do mecanicismo ao selecionismo: uma breve contextualização da transição do behaviorismo radical

Psicologia: Teoria e Pesquisa
O behaviorismo radical, como filosofia da ciência do comportamento formulada por B. F. Skinner, tem sido desde sua criação alvo de inúmeras críticas e tentativas de rotulação.
Robson Nascimento da Cruz, Eduardo Neves Pedrosa de Cillo   +1 more
doaj   +1 more source

S Skinner and Miss Alma

, 2004
Publicity postcard for Skid Skinner (Hector Skinner) and Miss Alma (Alma Morley, married in 1941 to become Skid Skinner) showing them riding the Wall of ...
Skinner, Alma
core