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A new variant of Brucella melitensis [PDF]

Clinical Microbiology and Infection, 2006
Brucella melitensis is highly pathogenic and constitutes a serious risk to public health. In Argentina, biovar 1 has been isolated from infected animals, but the Rev.1 strain vaccine is not authorised for use.
Maggy Grayon
exaly   +2 more sources

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Characteristics of B. melitensis versus B. abortus bacteraemias

Journal of Infection, 2005
To determine the epidemiological and the clinical characteristics of bacteremic brucellosis.A prospective study, performed in the First Infectious Diseases Clinic of Ankara Numune Education and Research Hospital. All the patients had positive culture result for Brucella spp.Fifty-four acute bacteremic brucellosis cases were included.
Basak Dokuzoguz, Nurcan Baykam, Selçuk Kılıç   +2 more
exaly   +3 more sources

Genome-Wide Analysis of the Response of Brucella melitensis NI to Polymyxin B

Current Pharmaceutical Biotechnology, 2021
Background: The ability of pathogenic bacteria to survive Antimicrobial Peptides (AMPs) in various host niches may contribute to their virulence. Polymyxin B is a cationic AMP, and polymyxin drugs are considered to be the "last line of defense" in the clinical treatment of bacterial infections.
Zhen Wang, Jiawei Wang, Jie Cheng, Xiaowen Yang, Hai Jiang, Qingmin Wu   +5 more
openaire   +2 more sources

Evaluation of Brucella melitensis B115 as rough-phenotype vaccine against B. melitensis and B. ovis infections

Vaccine, 2008
Brucella melitensis strain Rev1 is used as vaccine for the prophylaxis of brucellosis in sheep and goats. Because of its smooth phenotype, however, it induces antibodies directed to the O-polysaccharide (O-PS) of the lipopolysaccharide (LPS), thus unabling to distinguish between vaccinated and infected animals.
R, Adone, M, Francia, F, Ciuchini
openaire   +2 more sources

Protective role of antibodies induced by Brucella melitensis B115 against B. melitensis and Brucella abortus infections in mice

Vaccine, 2012
It has been demonstrated that antibodies specific for O-PS antigen of Brucella smooth strains are involved in the protective immunity of brucellosis. Since the rough strain Brucella melitensis B115 was able to protect mice against wild Brucella strains brucellosis despite the lack of anti-OPS antibodies, in this study we evaluated the biological ...
Rosanna, Adone, Massimiliano, Francia, Claudia, Pistoia, Paola, Petrucci, Michele, Pesciaroli, Paolo, Pasquali   +5 more
openaire   +2 more sources

Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization

Vaccine, 2007
bp26 and trigger factor (Tf) DNA vaccines have previously been shown to protect against Brucella infection. In this study, purified bp26 and Tf proteins were tested in BALB/c mice for immunity and protection. The results showed that intranasal (i.n.) immunization with bp26 and Tf in conjunction with cholera toxin (CT) adjuvant elicit both elevated ...
Xinghong, Yang, Nancy, Walters, Amanda, Robison, Theresa, Trunkle, David W, Pascual   +4 more
openaire   +2 more sources

Identification of Brucella abortus, B. canis, B. melitensis, and B. suis by carbon substrate assimilation tests

Veterinary Microbiology, 2001
By using the results of seven carbon substrate assimilation tests from the Biotype 100 system (bioMérieux, Marcy-l'Etoile, France), we correctly identified 79 (85.9%) of 92 Brucella strains tested. The specificity of the method varied from 97.4 to 100% depending on the species.
A, López-Merino, D L, Monnet, I, Hernández, N L, Sánchez, J M, Boeufgras, H, Sandoval, J, Freney   +6 more
openaire   +2 more sources

Serological diagnosis of bovine brucellosis using B. melitensis strain B115

Journal of Microbiological Methods, 2015
Bovine brucellosis is diagnosed by official tests, such as Rose Bengal plate test (RBPT) and Complement Fixation test (CFT). Both tests detect antibodies directed against the lipolysaccharide (LPS) of Brucella cell wall. Despite their good sensitivity, those tests do not discriminate between true positive and false positive serological reactions (FPSR),
CORRENTE, Marialaura, DESARIO, COSTANTINA, Antonio Parisi, GRANDOLFO, ERIKA, Domenico Scaltrito, Gesualdo Vesco, Valeriana Colao, BUONAVOGLIA, Domenico   +7 more
openaire   +3 more sources

Immunological responses and protective efficacy against Brucella melitensis induced by bp26 and omp31 B. melitensis Rev.1 deletion mutants in sheep

Vaccine, 2007
The commonly used live attenuated vaccine in ovine brucellosis prophylaxis is Brucella melitensis Rev.1. This vaccine is known to induce antibody responses in vaccinated animals indistinguishable by the current conventional serological tests from those observed in challenged animals.
Jacques, Isabelle, Verger, Jean-Michel, Laroucau, Karine, Grayon, Maggy, Vizcaíno, Nieves, Peix, Alvaro, Cortade, Fabienne, Carreras, Florence, Guilloteau, Laurence   +8 more
openaire   +3 more sources

Bacteriological and molecular investigation of B. melitensis in dairy cows in Iran

Comparative Clinical Pathology, 2010
It is extremely important to investigate the presence of Brucella melitensis as a nonspecific and heterogeneous agent in dairy cows in Iran due to mixed populations of sheep, goats, and cattle. B. melitensis from infected sheep or goat herds may be introduced into the cattle population in this area. Hence, it is essential to obtain epidemiological data
Hassan Sharifiyazdi, Masoud Haghkhah, Ali Mohammad Behroozikhah, Ebrahim Nematgorgani   +3 more
openaire   +1 more source